Microbial Electrosynthesis electrosynthesis holds the promise of sustainable chemical production. In article number 2203480, Guillermo C. Bazan and co-workers show that 3D living biocomposites integrating electroactive bacteria with an n-type conjugated polyelectrolyte allow efficient long-range electron transfer from electrode to cells, thereby enabling microbial electrosynthesis. The one-step...

Invariant natural killer T cells (iNKT cells) are critical for host defense against a variety of microbial pathogens. However, the central question of how iNKT cells are activated by microbes has not been fully explained. The example of adaptive MHC-restricted T cells, studies using synthetic pharmacological α-galactosylceramides, and the recent discovery of microbial iNKT cell ligands have all...

Osteoclasts, the cells capable of resorbing bone, are derived from hemopoietic precursor cells of monocyte-macrophage lineage. The same precursor cells can also give rise to macrophages and dendritic cells, which are essential for proper immune responses to various pathogens. Immune responses to microbial pathogens are often triggered because various microbial components induce the maturation a...

Neutral red (NR) was utilized as an electron mediator in microbial fuel cells consuming glucose to study both its efficiency during electricity generation and its role in altering anaerobic growth and metabolism of Escherichia coli and Actinobacillus succinogenes. A study of chemical fuel cells in which NADH, NR, and ferricyanide were the electron donor, the electronophore, and the electron acc...

The human body is colonized by at least the same number of microbial cells as it composed cells, and most these microorganisms are located in gut. Though interplay between gut microbiome host has been extensively studied, how interacts with enteric nervous system remains largely unknown. To date, a physiologically representative vitro model to study microbiome-nervous interactions does not exis...

it has been known for years that microbial surface active agents have a wide range of applications not only in oil spill environment but also in many industries. their properties including: (i) changing surface active phenomena, such as lowering of surface and interfacial tensions, (ii) wetting and penetrating actions, (iii) spreading, (iv) hydrophylicity and hydrophobicity actions, (v) microbi...

We demonstrate a novel one-pot biocatalytic process for the preparation of versatile chemical intermediate, 2,6-bis(hydroxymethyl)pyridine, from naturally-occurring 2,6-lutidine using recombinant microbial whole cells as catalysts.