coronary heart disease has been one of the main threats of human health. coronary angiography is taken as the “gold standard” for the assessment of coronary artery disease. but sometimes, the images are difficult to interpret visually because of the crossing and overlapping of the vessels in the angiograms. vessel extraction from x-ray angiograms has been a challenging problem for several years...

BACKGROUND: There is an urgent need for better detection and understanding of vascular abnormalities at the micro-level, where critical nourishment cellular metabolic changes occur. This especially case structures such as midbrain hippocampus, both feeding draining vessels are quite small. The hippocampus a complex grey matter structure that plays important role in spatial episodic memory. It c...

In this paper, we extend our published work [Cao et al., 2011] on methods to support the analysis of both vessel bed segmentation and microvascular centreline extraction in co-registered retinal angiogram sequences. These tools should allow researchers and clinicians to estimate and assess the (micro-)vessel diameter, capillary blood volume and microvascular topology for early stage disease det...

Occlusions of the retinal veins and arteries, associated with diseases such as hypertension and arteriosclerosis, are a major cause of severe and irreversible loss of vision. Treatments for retinal vascular diseases have been unsatisfactory owing in part to the difficulty of delivering drugs to the site of disease within the eye. In this article, we demonstrate that a new device, the vapor bubb...