Establishing and using traceability and provenance between different models is a very important issue in complex software systems. Traceability in the small (local traceability) handles the trace information between model elements. Traceability in the large (global traceability) handles traceability information between models as a whole. Current solutions are more or less adhoc approaches that ...

In a context of cryosphere degradation caused by climate warming, rock temperature is one the main driving factors rockfalls that occur on high-elevation mountain slopes. order to improve knowledge this critical relationship, it necessary increase measurement capability and its variability in different lithological slope/aspect conditions, also local scale studies, increasing quality comparabil...

The measurement of creatinine in serum is a key indicator of glomerular function of the kidney and its pivotal role in this evaluation has been further increased by recommendations issued by nephrology societies for using equations to estimate the glomerular filtration rate (GFR) [1]. In 2006 the reference system for the measurement of serum creatinine, using suitable higher-order reference mat...

There is currently interest in the digitalisation of metrology because technologies that can measure, analyse, and make critical decisions autonomously are beginning to emerge. The notions metrological traceability measurement uncertainty should be supported, following recommendations Guide Expression Uncertainty Measurement (GUM). However, GUM offers no specific guidance. Here, we report on a ...

BACKGROUND The availability of commutable calibrator materials may ease considerably the task of harmonizing assay results and ensuring their traceability to reference procedures. We sought to verify the commutability of potential calibrator materials and evaluate their effectiveness in harmonizing LDH results by 2 measurement methods. METHODS We measured LDH in 109 serum samples and 31 mater...

Terrestrial laser scanners (TLS) are a class of 3D imaging systems that produce a 3D point cloud by measuring the range and two angles to a point. The fundamental measurement of a TLS is range. Relative range error is one component of the overall range error of TLS and its estimation is therefore an important aspect in establishing metrological traceability of measurements performed using these...

Within the framework of the European Metrological Research Program (EMRP) IND04 MetroMetal 'Ionizing radiation metrology for the metallurgical industry', joint research carried out by 14 metrological institutions from countries within the European Union and the company ENVINET, questions concerning the determination of radioactivity in samples relevant to the metallurgical industry were resolve...

Nowadays, a lot of time and resources are used to determine the quality of goods and services. As a consequence, the quality of measurements themselves, e.g., the metrological traceability of the measured quantity values is essential to allow a proper evaluation of the results with regard to specifications and regulatory limits. This requires knowledge of the measurement uncertainties of all qu...

The central importance of HbA(1c) in monitoring glycaemic control was highlighted by the Diabetes Control and Complications Trial (DCCT) which showed that improved glycaemic control, as monitored by HbA(1c), delayed the onset of diabetic complications. Following this publication the issue of international standardisation of glycated haemoglobin (GHb) measurements became an important objective. ...

A mass spectrometry-based antibody selection procedure was developed to evaluate optimal 'capture' monoclonal antibodies that can be used in a variety of analytical measurement applications. The isotope-dilution liquid chromatography-tandem mass spectrometry (ID LC-MS/MS) methodology is based on the use of multiple-reaction monitoring of tryptic peptide fragments derived from protein antigens. ...