Paroxysmal nonepileptic events are episodic changes in behavior, sensation, or consciousness that similar to epileptic seizures but not associated with abnormal ictal brain electrophysiological discharges. Here, a case treated as seizure was presented order draw attention paroxysmal differential diagnosis.
 A 4 years old girl sent our hospital the diagnose of status epilepticus due change ...

To the Editor: The prescription of medicines like methylphenidate for Attention Deficit Hyperactivity Disorder (ADHD) has increased ten-fold since 2004 in Denmark, and now amounts to approximately 12 million defined daily doses per year. Testing the patients for drug abuse is highly relevant, because the link between ADHD and drug abuse continues to be an area of interest in both adolescent and...

Bortoluzzi, E., Roella, C , Bortoluzzi, S. L., and Montoli, E. (1963). Methylphenidate in the treatment of shivering. Anesth. Analg. (Clcvc), 42, 325. Brichard, G., and Johnstone, M. (1970). The effect of methylphenidate (Ritalin) on post-halothane muscle spasticity. Br. J. Anaesth., 42, 718. Maxwell, R. A., Sylwestrowicz, H. D., Holland, R., Schneider, F., and Daniel, A. I. (1961). Some action...

Study queStion Is methylphenidate beneficial or harmful for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents? MethodS Electronic databases were searched up to February 2015 for parallel and crossover randomised clinical trials comparing methylphenidate with placebo or no intervention in children and adolescents with ADHD. Meta-analyses and trial seque...

Dopamine signals through D1-like and D2-like receptors, which can stimulate or inhibit, respectively, neuronal activity. Here we assessed the balance between D1 or D2 receptor signaling in the human brain and how it is affected in alcoholism. Using PET, we measured the relationship between changes in dopamine and brain glucose metabolism induced by methylphenidate in controls and alcoholics. We...

STUDY OBJECTIVES To assess the prevalence of illicit methylphenidate use among undergraduate college students at a large university, and to identify alcohol and other drug use behaviors, as well as the negative consequences and risk factors, associated with illicit methylphenidate use. DESIGN Internet survey. SETTING Large public university. SUBJECTS Thirty-five hundred randomly selected ...

OBJECTIVE Methylphenidate hydrochloride is the most widely used medication for treatment and management of attention-deficit hyperactivity disorder. However, the chronic effects of methylphenidate hydrochloride on anxiety- and depressive-like rat behaviors remain poorly investigated. In this context, the present study evaluated the effects of treatment with methylphenidate hydrochloride on anxi...

Methylphenidate as a psycho stimulant drug has been prescribed in neuropsychiatric disorders to increase cognition and attention therefore is a medication of choice for attention-deficit/hyperactivity disorder however long-term administration of central nervous system stimulant produces tolerance on cognitive behavior. Previously it has been shown that long-term psychostimulant administration i...

Methylphenidate, a drug widely used for attention deficit hyperactivity disorder in children, may affect neuronal function differently in young and adult subjects, particularly in the prefrontal cortex, a brain structure that does not fully develop until adulthood. We compared the impact of development on the effects of methylphenidate on single unit electrical activity and mRNA expression of t...

objectives : the aim of this randomized clinical trial was to assess the efficacy of memantine versus methylphenidate in the treatment of children with attention deficit hyperactivity disorder. method : forty participants (34 boys and 6 girls) aged 6-11 who were diagnosed with attention deficit hyperactivity disorder based on (dsm-iv-tr) criteria were selected for this study. the participants w...