نتایج جستجو برای: methylenetetrahydrofolate reductase gene
تعداد نتایج: 1173819 فیلتر نتایج به سال:
It is now well-established that folic acid, taken peri-conceptionally, can reduce the risk of neural tube defects (NTDs). Recent work has demonstrated that an abnormality of homocysteine metabolism is a critical factor. The gene for 5,10 methylenetetrahydrofolate reductase, an enzyme important in homocysteine metabolism, was studied in relation to NTDs. To determine the frequency of the allele ...
The effects of 5,10-Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on human bone marrow-derived mesenchymal stem cells (hBM-MSCs) viability, morphology, physiology and differentiation capacity were investigated in this study. For purpose, primary hBM-MSCs with wild type (WT, C/C), heterozygote (HTZ, C/T) homozygote (HMZ, T/T) for the MTHFR gene obtained ethical committee permiss...
BACKGROUND Folate metabolism pathway genes have been examined for association with neural tube defects (NTDs) because folic acid supplementation reduces the risk of this debilitating birth defect. Most studies addressed these genes individually, often with different populations providing conflicting results. OBJECTIVES Our study evaluates several folate pathway genes for association with huma...
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