The global production of the greenhouse gas methane by methanogenic archaea reaches 1 billion tons per annum. The final reaction releasing methane is catalyzed by the enzyme methyl-coenzyme M reductase. The crystal structure of methyl-coenzyme M reductase from Methanobacterium thermoautotrophicum revealed the presence of five modified amino acids within the alpha-subunit and near the active sit...

Young and adult rats received intracranial injections of [33P]orthophosphoric acid. The time course of the appearance and decay of the radioactive label on basic proteins in isolated myelin was followed for 1 mo. Incorporation was maximal by 1 h, followed by a decay phase with a half-life of approximately 2 wk. However, radioactivity in the acid-soluble precursor pool (which always constituted ...

A number of liquid crystal dimers have been synthesised and characterised containing secondary or tertiary (N-methyl) benzanilide-based mesogenic groups.

Thermal behavior including the cold crystallization of a Schiff base complex bearing two methyl groups was investigated. Additionally, effect alkoxy chain length studied.

I. The role of carboxyl groups in the binding of specific carbohydrates to concanavalin A, the phytohemagglutinin of the jack bean, has been studied using two techniques: (I) H + titration in the presence and absence of methyl a-D-mannopyranoside, a specifically bound carbohydrate ligand and (2) chemical modification of the protein carboxyl groups employing glycine methyl ester and a water-solu...

In this work, the effect of ligand's length on interaction energy of six oximes, A [2-(hydroxyimino)-N-((1-(2-(2-((hydroxyimino)methyl)-1H-imidazol-1-yl)ethyl)-1H-1,2,3-triazol-4-yl)methyl)acetamide], B [2-(hydroxyimino)-N-((1-(3-(2-((hydroxyimino)methyl)-1H-imidazol-1-yl)propyl)-1H-1,2,3-triazol-4-yl)methyl)acetamide], C [2-(hydroxyimino)-N-((1-(4-(2-((hydroxyimino)methyl)-1H-imidazol-1-yl)but...

background: betaine has been shown to be antioxidantand methyl donor effects in our recent studies. objectives: inthe present study, the antioxidant and methyl donor properties ofbetaine in levodopa/benserazide-mediated hyperhomocysteinemiaand levodopa-induced oxidative stress in rat's kidney wereexamined. methods: sprague-dawley male rats were dividedinto levodopa (ld), betaine (bet.), levodop...