A range of hydrogels were prepared by solution polymerization of methacrylic acid, poly(ethyleneglycol) methyl ether methacrylate (M.W. 475 g/mol) and poly(ethyleneglycol) dimethacrylate (as the cross-linking, M.W. 550 or 875 g/mol) in various proportions. The effects of methacrylic acid/ poly(ethyleneglycol) methyl ether methacylate concentration ratios as well as cross-linking concentration i...

A series of sorbents containing various amounts of borate groups were prepared by chemical immobilization ofP-aminoethylphenylboric acid on a copolymer- treated organosilane spacer glass plates. It was found thatbaker's yeast cells selectively adhered to these supports. Yeast cells stained with procion red HE-3B formeddenser and more stable layer on the copolymer-grafted supports compared onto ...

Graft polymerizations of vinyl acetate onto granular corn starch were initiated by cobalt-60 irradiation of starch-monomer-water mixtures. and ungrafted poly(vinyl acetate) was separated from the graft copolymer by benzene extraction. Conversions of monomer to polymer were quantitative at a radiation dose of 1.0 IvIrad. However, over half of the polymer was present as ungrafted poly(vinyl aceta...

Molecularly imprinted polymers bearing atrazine transforming activity were prepared by using newly designed templates that are atrazine analogues attached with an allyl or a styryl group via a disulfide bond at the 6-position, methacrylic acid as a functional monomer and styrene/divinylbenzene as crosslinkers. After polymerization, the disulfide bond was reduced to remove the atrazine moiety fr...

The primary goal of bioadhesive controlled drug delivery is to localize a delivery device within the body to enhance the drug absorption process in a site-specific manner. An important contributor to good adhesion is the presence of molecular adhesion promoters such as polymer-tethered structure (e.g., poly(ethylene glycol) chains grafted to crosslinked networks) or even linear chains which are...

ABSTRACT Mixed-metal oxo clusters Cu4Ti5O6(OOCR)16 (OOCR = methacrylate, propionate) were obtained by reaction of titanium alkoxides and copper carboxylates with propionic or methacrylic acid. GRAPHICAL ABSTRACT

It has been suggested that polymer coating might retard jejunal absorption of 5-amino salicylic acid (5-ASA) and thus promote delivery to its colonic site of action. Twenty three patients with active (nine), or quiescent (14) ulcerative colitis were given either uncoated or coated 5-ASA (Asacol) 400 mg qds for one to three weeks, after which they ingested five 1.5 ml dialysis membrane sachets w...