Hepatoblastoma (HB) is a rare tumor of infancy and childhood manifesting with hepatomegaly and abdominal distention. It is seen with increased frequency in association with congenital hemihypertrophy and renal anomalies. Metastases to other organs, including the lungs, lymph nodes and even ovaries is well known. But cerebral metastasis of this tumor, especially in the absence of metastasis ...

Mestastatic prostate cancer cells (MPCCs) frequently metastasize to bone, which is a “favorite soil” for colonization and proliferation of MPCCs. Prostate cancer bone mestastasis is tightly associated with tumor-induced bone lesions, most commonly caused from the etiological imbalance between osteoblastic bone formation and osteoclastic bone resorption, and from the anti-tumor immune response. ...

objective(s): bonenavi, a computer-aided diagnostic system, is used in bone scintigraphy. this system provides the artificial neural network (ann) and bone scan index (bsi) values. ann is associated with the possibility of bone metastasis, while bsi is related to the amount of bone metastasis. the degree of uptake on bone scintigraphy can be affected by the type of bone metastasis. therefore, t...

introduction: squamous cell carcinoma of the oral cavity is one of the most important and common types of head and neck malignancy, with an estimated rate of 4% among all human malignancies. the aim of this study was to determine the association between expression of matrix metalloproteinase 2 and 9 and the clinicopathological features of oral squamous cell carcinoma (oscc).   materials and met...

a 38 years old male worker presented with an advanced left side retroperitoneal mass, with metastatic involvement of 11th thoracic vertebra (t11) and resultant paraparesia and paresthesia . the histopathologic examination and immunohistochemical analysis confirmed the diagnosis of paraganglioma. decompression laminectomy and fixation of involved vertebra resulted to considerable symptomatic rel...

introduction: endometrial cancer is the most common pelvic malignancy in women. approximately 7,000 women die from this disease every year. although most patients can be treated with appropriate therapies, there is insufficient data regarding the choice of the best adjuvant therapy after a surgical procedure in advanced endometrial cancer cases. it seems that radiotherapy or chemotherapy alone ...

metastasis of gastroesphageal junction (gej) adenocarcinoma in skeletal muscle is rare and primary sites for skeletal muscle metastases are usually lung, renal and colorectal cancer. we have encountered with the first case report of solitary psoas muscle metastasis of gej adenocarcinoma. here we describe a 65 years old man was diagnosed with gej adenocarcinoma in tertiary hospital, tehran, iran...

introduction: involvement of the skeleton can cause an excruciating pain in two-thirds of terminal patients with a history of malignancy. due to several limitations of other therapies, such as analgesics, bisphosphonates, chemotherapy, hormonal therapy and external beam radiotherapy; bone-seeking radiopharmaceuticals have an important role in palliation of pain from bone metastases. although th...

background: the sentinel lymph node (sln) is defined as the first chain node in the lymphatic basin that receives primary lymphatic flow. if the sln is negative for metastatic disease, then other nodes are expected to be disease-free. sln techniques have been extensively applied in the staging and treatment of many tumors, including melanoma, breast and vulvar cancers. this study aims to evalua...