Anesthesia for major head and neck surgery is historically heavily reliant on opioids with deleterious consequences. We reported a case of patient history heroin abuse submitted to tongue carcinoma excision, followed by free-flap reconstruction under opioid-free anesthesia. used propofol total intravenous anesthesia perfusions ketamine, dexmedetomidine, lidocaine, magnesium sulfate analgesia, c...

Pyrazolone is a five-membered lactam ring containing two Nitrogens and one ketonic group in its structure. Numerous pyrazolone derivatives were exhibited with diverse biological, pharmacological, chemical applications. When pyrazolones discovered, they only known as NSAIDs but recent times play versatile role several complications like cerebral ischemia, cardiovascular diseases, antibacterial, ...

The number of caesarean sections (CS) in comparison with spontaneous deliveries is growing in most industrial countries, which raises economic and medical questions. The pathophysiology of post-CS pain includes both somatic and visceral components, and may give rise to pain intensity of 7, using the Verbal Rating Scale 0–10. Despite a variety of analgesic options, the quality of post-CS pain co...