The origin of ovarian epithelial tumors is still indistinct. Müllerian and coelomic hypothesis are controversial. Recently, there is also a small number of reports that tubo-peritoneal junction may play an important role in the development of tubo-ovarian tumors. Therefore, we aimed to investigate the relationship between tumors originating from Mullerian epithelium and peritoneal mesothelium, ...

Human placental alkaline phosphatase (HPLAP), carcinoembryonic antigen (CEA), and cancer antigen 125 (CA 125) were localized immunohistochemically in paraffin sections of normal lung tissue from 16 patients, using monoclonal antibodies and an indirect avidin-biotin-peroxidase staining procedure. HPLAP and CEA were present in epithelial cells of respiratory bronchioli and alveolar type I pneumoc...

The mesothelium, the lining of the coelomic cavities, and the urothelium, the inner lining of the urinary drainage system, are highly specialized epithelia that protect the underlying tissues from mechanical stress and seal them from the overlying fluid space. The development of these epithelia from simple precursors and the molecular characteristics of the mature tissues are poorly analyzed. H...

The placenta facilitates nutrient and gas exchanges between the mother and growing fetus. It does this through highly branched embryonic blood vessels called villi. In the mouse, villi start to form when the allantois attaches to the chorion. This attachment is mediated through a thin layer of mesothelium on the chorion, which becomes indistinguishable from the allantoic cells after attachment....

The placenta facilitates nutrient and gas exchanges between the mother and growing fetus. It does this through highly branched embryonic blood vessels called villi. In the mouse, villi start to form when the allantois attaches to the chorion. This attachment is mediated through a thin layer of mesothelium on the chorion, which becomes indistinguishable from the allantoic cells after attachment....

The peritoneal mesothelium exhibits a high regenerative ability. Peritoneal regeneration is concomitant with the appearance, in the coelomic cavity, of a free-floating population of cells whose origin and functions are still under discussion. We have isolated and characterized this cell population and we have studied the process of mesothelial regeneration through flow cytometry and confocal mi...