PURPOSE To compare pupil sizes measured with the Colvard pupillometer, Procyon pupillometer, and NIDEK OPD-Scan. METHODS Pupil diameter was measured in 90 consecutive eyes from 55 patients under mesopic and scotopic light conditions with all three instruments. RESULTS The mean scotopic pupil diameter was 6.3+/-0.98 mm with the Colvard pupillometer and 6.45+/-1.01 mm with the Procyon pupillo...

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are cation-selective channels present in retina, brain and heart. The activity of HCN channels contributes to signal integration, cell excitability and pacemaker activity. HCN1 channels expressed in photoreceptors participate in keeping light responses transient and are required for normal mesopic vision. The subcellular localiz...

PURPOSE Automated scotopic, mesopic, and photopic perimetry are likely to be important paradigms in the assessment of emerging treatments of retinal diseases, yet our knowledge of the photoreceptor mechanisms detecting targets under these conditions remains largely dependent on simian data. We therefore aimed to establish the photoreceptor/postreceptoral mechanisms detecting perimetric targets ...

This control-matched comparative study evaluated changes in contrast sensitivity after Zyoptix tissue-saving (TS) LASIK and Planoscan standard LASIK (Technolas 217z, Bausch & Lomb) for myopia 6 months postoperatively. 102 TS LASIK-treated eyes were matched with 102 standard LASIK-treated eyes (divided into low, moderate, and high groups). There were no significant differences in refraction outc...

BACKGROUND Keratoconus (KC) is usually a bilateral corneal ectatic disease. For significant asymmetric presentation (so called unilateral KC), the fellow eye has the mildest and earliest form of the disease, which is typically called forme fruste keratoconus. The aim of this study was to evaluate the sensitivity and specificity of parameters derived from a Scheimpflug imaging system (Pentacam) ...

New World monkeys exhibit a color vision polymorphism. It results from allelic variation of the single-locus middle-to-long wavelength opsin gene on the X chromosome. Females that are heterozygous for the gene possess trichromatic vision. All other individuals possess dichromatic vision. The prevailing hypothesis for the maintenance of the color vision polymorphism is through a consistent fitne...

To verify the changes of mesopic and photopic contrast sensitivity function of sound eye whose visual acuity was kept the same after occlusion therapy in the amblyopic children. Fourteen sound eyes of amblyopic children (mean; 7.67 years; S.D., 1.50 years) who kept their visual acuity the same after the occlusion therapy were tested. The children had 6 hours of part-time patch therapy for 3 mon...