*Corresponding author E mail: [email protected] J. Pharm. BioSci. 3(2013) 114-123 Abstract Pyrazole is five membered heterocyclic rings which is versatile lead compound for designing potent bioactive agent. The interesting groups of this compound has diverse biological activities such as antimicrobial, anti-inflammatory, anticancer, analgesic, anticonvulsant, anthelmintic, antioxidant an...

In the title compound, C(18)H(15)NO(4), the benzene rings form quite different dihedral angles [16.07 (1) and 59.50 (1)°] with the central pyrrole ring, indicating a twisted mol-ecule. Conjugation is indicated between the five- and six-membered rings by the lengths of the C-C bonds which link them [1.462 (3) and 1.477 (3) Å]. The most prominent feature of the crystal packing is the formation of...

The title compound, C(41)H(70)O(12)·CH(4)O, was prepared by microbial transformation. Within the steroid skeleton of the mol-ecule, three six-membered rings exhibit a chair conformation, while the five -membered ring adopts an envelope conformation. The two pyranosyl rings also adopt chair conformations. The mol-ecules are held together by an extensive O-H⋯O hydrogen-bonding network.

A twist is evident in the title compound, C(21)H(21)N(3)O(2), the dihedral angle between the terminal six-membered rings being 29.46 (10)°; the linked five- and six-membered rings are coplanar [1.30 (11)°]. The carbonyl O atom accepts intra-molecular hydrogen bonds from the adjacent hy-droxy and amine groups. The three-dimensional crystal packing is achieved through C-H⋯π inter-actions.

The title compound, C(20)H(20)O(5), was synthesized from the reaction between 3-methoxysalicaldehyde and 1,3-cyclo-hexa-nedione in the presence of palladium(II) chloride. The two fused xanthene rings and one of the six-membered cyclo-hexane rings adopt envelope conformations, while the other six-membered cyclo-hexane ring is in a chair conformation. The mol-ecular packing is stabilized by weak ...

In the title compound, C(14)H(20)O(9), the six-membered pyran and the five-membered dioxalane rings adopt chair and twisted conformations, respectively. In the crystal, the mol-ecules are linked by C-H⋯O inter-actions.

In the title compound, C(15)H(26)O(6)Si, the dioxa six-membered ring bonded to the myo-inositol skeleton is in a boat conformation while the rest of the six-membered rings adopt chair conformations.

The title compound, C16H24Cl2O, is built up from two fused six- and seven-membered rings which bear a di-chloro-cyclo-propane group and an ep-oxy group, respectively. In the mol-ecule, the six-membered ring adopts an envelope configuration with the C atom linking the ep-oxy ring at the flap, while the seven-membered ring adopts a boat-sofa conformation.

The title compound, C(31)H(50)O, a tetra-cyclic triterpene, was isolated from Ainsliaea henryi. The mol-ecule contains a three-membered ring, a five-membered ring, which exhibits an envelope conformation, and three six-membered rings, which adopt chair conformations.