نتایج جستجو برای: melatonin
تعداد نتایج: 10831 فیلتر نتایج به سال:
BACKGROUND Melatonin inclusion into in vitro oocyte maturation (IVM) protocols has been suggested because it possesses a powerful free radical scavenger capability that improves the quality of the oocyte used in in vitro embryo production (IVP). The aim of our study was to investigate the presence of melatonin membrane receptors (MT1and MT2) and MT3, which is the melatonin binding site of NQO2 ...
*Corresponding author: Maryam Tavakoli M.D, Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Email: [email protected] Melatonin is a hormone produced in the pineal gland. Melatonin is produced of tryptophan and serotonin and is metabolized to 6-hydroxyl melatonin in the liver (1-3). Melatonin is a highly important antioxidant. Free radicals damages cells...
Melatonin and its analog 5-MCA-NAT (5-methylcarboxyamino-N-acetyl tryptamine) are active compounds reducing intraocular pressure (IOP). This action is mediated through MT2 and the putative MT3 melatonin receptor, producing a transient reduction of IOP that lasts for a few hours and has not yet been characterized. The use of melatonin and its analog are causing a decrease in chloride efflux from...
no abstract
اثر ملاتونین بر شاخصهای چاقی و تغییرات متابولیک ناشی از رژیم غذایی با فروکتوز بالا در موش صحرایی نر
Background : The Obesity and metabolic diseases appears to have emerged largely and epidemically because of changes in our diet and life style. The aim of this study was to investigate the effects of melatoninon plasma glucose, uric acid, insulin, HOMA, body weight gain and Liver and kidney histology in fructose fed rats. Methods: In this experimental study, 24 male Wistar rats were used. A...
background: damage to spermatogenic and fertility disorders are among major side effects of chemotography drugs such as busulfan. to reduce the side effects of these drugs different methods such as protecting and fixing germinal cell epithelium, while employing chemotherapy are used. the aim of this study was to investigate the effect of exogenous melatonin on the treatment of oligospermic in s...
Influence of oxidative stress on oocyte quality and protective role of melatonin as an antioxida Poor oocyte quality is an important cause of female infertility. Reactive oxygen species (ROS) are produced within ovarian follicles, especially during ovulation process, and it is thought that increased ROS activity may be a cause of impaired oocyte maturation. Pineal hormone, melatonin, is detecte...
Melatonin (N-acetyl-5-methoxytryptamine) is a highly conserved molecule that is not exclusive to the animal kingdom and its presence in plants has been confirmed by numerous studies. Melatonin has delayed flowering in some day-sensitive plants. When spinach enters the reproduction phase, its nutritional value is markedly reduced. This experiment was conducted to evaluate the effects of melatoni...
Background: Neuroinflammation and oxidative stress play a pivotal role in the diabetic neuropathic pain. The aim of this study was to evaluate the effect of aerobic exercise with melatonin on RAGE gene expression and some indicators of oxidative stress in rats with diabetic neuropathic pain Methods: Forty 8-week-old male Wistar rats (weight range 204 ± 11.3 g) were randomly divided into five o...
Background: Peripheral nerve injury (PNI) is a common condition that compromises motor and sensory functions. Peripheral nerves are known to have regenerative capability and the pineal hormone, melatonin, is known to aid nerve regeneration. However, the role of Schwann cells and the pathways involved remain unclear. Thus, the aim of this study is to identify the effects of melatonin on Schwann ...
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