The ubiquitin proteasome system is involved in degradation of old or damaged sarcomeric proteins. Most E3 ubiquitin ligases are associated with cullins, which function as scaffolds for assembly of the protein degradation machinery. Cullin 3 uses an adaptor to link to substrates; in Caenorhabditis elegans, one of these adaptors is the BTB-domain protein MEL-26 (maternal effect lethal). Here we s...

Recent changes in the Music Encoding Initiative (MEI) have transformed it into an extensible platform from which new notation encoding schemes can be produced. This paper introduces MEI as a document-encoding framework, and illustrates how it can be extended to encode new types of notation, eliminating the need for creating specialized and potentially incompatible notation encoding standards.

In rice (Oryza sativa), hybrids between indica and japonica subspecies are usually highly sterile, which provides a model system for studying postzygotic reproductive isolation. A killer-protector system, S5, composed of three adjacent genes (ORF3, ORF4, and ORF5), regulates female gamete fertility of indica-japonica hybrids. To characterize the processes underlying this system, we performed tr...

D ow Dominant climatic factors controlling the lifetime peak intensity of typhoons are determined from six decades of Pacific typhoon data. We find that upper ocean temperatures in the low-latitude northwestern Pacific (LLNWP) and sea surface temperatures in the central equatorial Pacific control the seasonal average lifetime peak intensity by setting the rate and duration of typhoon intensific...

“Dascălii mei” (“My mentors”) is a book of memoirs, which evokes different aspects of the education and remarkable teachers and professors, from kindergarten to university. The author – Prof. Dr. Sorin Nicu Blaga – proves, once again, his profound respect and admiration for his masters. It is useful to mention that the author's concern in the field of history and, particularly, in the medical h...

Wei-Chih Kan1,2, Chih-Chiang Chien1,2, Yi-Hua Lu1, Jyh-Chang Hwang1, Shih-Bin Su3,4 and Hsien-Yi Wang1,5 1Department of Nephrology, Chi-Mei Medical Center, Tainan 2Chung Hwa University of Medical Technology, Tainan 3Department of Family Medicine, Chi-Mei Medical Center, Tainan 4Department of Biotechnology, Southern Taiwan University, Tainan 5Chia Nan University of Pharmacy and Science, Tainan T...

This paper provides a technical introduction to the Music Encoding Initiative (MEI) DTD currently under development by the author. It is consciously modeled on the highly successful Text Encoding Initiative (TEI) DTD. The primary purpose of the MEI DTD is the creation of a comprehensive yet extensible standard for the encoding and transmission of music documents in electronic form.

1. In an experiment twenty-four cross-bred does were used, six in each of four physiological states: non-pregnant (NP), pregnant (P), lactating (L) or concurrently pregnant and lactating (CPL). They were offered a diet of high nutrient density (crude protein (nitrogen x 6.25) 272 g/kg dry matter (DM), metabolizable energy 15.5 MJ/kg DM) at one of two intakes on a scale based on metabolic body-w...

DNA repair-defective alleles of the mei-9, mei-41, mus-104 and mus-101 loci of Drosofihila melanogaster were introduced into stocks bearing the UZ and SZ marker sets. Males with the UZ marker set, z1 (zesle allele) and w + ( ' ~ ) (genetically unstable white allele presumably caused by a transposable element), or the SZ marker set, z ' and w + ~ (semistable white allele caused by partial duplic...

In rice (Oryza sativa), hybrids between indica and japonica subspecies are usually highly sterile, which provides a model system for studying postzygotic reproductive isolation. A killer-protector system, S5, composed of three adjacent genes (ORF3, ORF4, and ORF5), regulates female gamete fertility of indica-japonica hybrids. To characterize the processes underlying this system, we performed tr...