نتایج جستجو برای: mega
تعداد نتایج: 7441 فیلتر نتایج به سال:
A decade ago, while managing the Computer Science Laboratory at Xerox Palo Alto Research Center, Mark Weiser envisioned a computer “so imbedded, so fitting, so natural, that we use it without even thinking about it” (“Creating the Invisible Interface,” Proc. 7th Ann. ACM Symp. User Interface Software and Technology, ACM Press, 1994, p. 1). Today, Weiser’s vision is coming to pass everywhere: ga...
PURPOSE Glutathione (GSH) is an important intracellular antioxidant in the brain. A number of studies report its measurement by localized 1 H spectroscopy using PRESS and STEAM. This study evaluates the reliability and accuracy of GSH measurements from PRESS at 3 Tesla (T) and compares the results to those obtained with MEGA-PRESS. METHODS Phantoms containing brain metabolites, identical exce...
Phylogenetic analysis is sometimes regarded as being an intimidating, complex process that requires expertise and years of experience. In fact, it is a fairly straightforward process that can be learned quickly and applied effectively. This Protocol describes the several steps required to produce a phylogenetic tree from molecular data for novices. In the example illustrated here, the program M...
The Department of Defense, like other government agencies and indeed the global business community, faces increasingly complex challenges that cannot be met by standalone systems. This has led to growing reliance on increasingly interoperable and interdependent systems that combine multiple organizational and functional capabilities to achieve an overarching mission. This is the motivation for ...
Purpose – Open-access mega-journals (OAMJs) represent an increasingly important part of the scholarly communication landscape. OAMJs, such as PLOS ONE, are large scale, broad scope journals that operate an open access business model (normally based on article-processing charges), and which employ a novel form of peer review, focussing on scientific “soundness” and eschewing judgement of novelty...
Using the Internet to facilitate business-to-business commerce promises many benefits, such as dramatic cost reductions and greater access to buyers and sellers. Yet little is known about how B2B e-commerce will evolve. The authors argue that changes in the financial services industry over the past two decades provide important clues. Exchanges, they say, are not the primary source of value in ...
Proof planning is a novel knowledge-based approach for proof construction, which supports the incorporation of mathematical knowledge and the common mathematical proof techniques of a particular mathematical eld. This paradigm is adopted in the mega proof development system, to provide support for the user. A considerable part of the proof construction and even sometimes the whole work can be u...
From the deglacial period to the mid-Holocene, North Africa was characterized by much wetter conditions than today. The broad timing of this period, termed the African Humid Period, is well known. However, the rapidity of the onset and termination of the African Humid Period are contested, with strong evidence for both abrupt and gradual change. We use optically stimulated luminescence dating o...
This paper examines the planning paradigm shift related to the contested “urban renaissance” mega-project in Downtown Seoul (Korea). Similar to other global cities, over the last few decades, different mega-projects have been successfully implemented in Seoul. These projects have been considered engines for urban renewals and transformation. This paper builds on the analysis of the failure and ...
Combining datasets across independent studies can boost statistical power by increasing the numbers of observations and can achieve more accurate estimates of effect sizes. This is especially important for genetic studies where a large number of observations are required to obtain sufficient power to detect and replicate genetic effects. There is a need to develop and evaluate methods for joint...
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