Case Report: A 19-year-old male with the diagnosis of syncope, tachycardia with arrhythmia, and chest pain was referred to the University Clinic of Cardiology for the echocardiography. Transthoracic echocardiography showed bicuspid aortic valve with normal left ventricular (LV) dimensions and normal systolic function. Mild thickening of the aortic valve cusps and mild aortic regurgitation was f...

BACKGROUND: The stroke is leading cause of death and severe disability worldwide. Atherosclerosis is responsible for over 30% of all ischemic strokes. It has been recently discovered that plaque morphology may help predict the clinical behavior of carotid atherosclerosis and determine the risk of stroke. The noninvasive imaging techniques have been developed to evaluate the vascular wall in an ...

Diabetic nephropathy (DN) remains the most common cause for end stage renal disease (ESRD) as the burden of diabetes increases worldwide [13]. The mechanisms of DN are not very clear, but the extensive investigation has documented the key role of the rennin angiotensin aldosterone system (RAAS) in the pathogenesis and pathophysiology of DN [4]. Accordingly, blockade of the RAAS is first-line th...

RESULTS: The total number of eosinophils was significantly increased in the group of asthma patients versus second and third group. We found that the presence of ECP demonstrate an ongoing inflammation, with or without clinical symptoms of asthma patients. There was significant difference between the values of ECP of asthma patients versus second and third group. Our results have shown that IL-...

Over the past 20 years, the requested informations for drugs safety and efficacy are expanded with data about patient results, cost and cost-effectiveness, which increased significantly the соsts of pharmaceutical companies. Direct comparisons must be carried out with other drug product and these pharmacoeconomic comparisons are called Phase IV or post-marketing studies. Cost analysis focuses o...

In the presented case report, we evaluated the mechanism of the external iliac, the common femoral and the superficial femoral arterial thrombosis secondary to total hip arthroplasty. A 75year-old female sufferd from 5.5 cm shorter left lower limb and same sade coxarthritis. Next day after arthroplasty and eqalisation of the lower limbs, an acute ishemia of the treated leg was presented. Multys...

RESULTS: 16.7% TB patients have not received any assistance when diagnosed with TB and 8.4% were treated badly by a member of the family or close friends because of the disease, consequences ranging from living the patient completely, refusal to talk or telling other people that the person is infected. An odd for such behavior were higher if the patient is male, married, have no formal educatio...

Environmental concerns have resulted in the search for environmentally friendly natural oils for use as mosquito larvacide. Methylated coconut oil has been found to be toxic to mosquito larvae. However, the use of methylated coconut oil is limited by resource constraints in rural communities in Papua New Guinea and other Pacific Island countries where coconut oil is produced by traditional meth...

Hypertrophic cardiomyopathy is an inherited heart muscle disease with an estimated prevalence in the adult population of 1:500. Owing to the autosomal dominant nature of this disease, persons who have a parent with hypertrophic cardiomyopathy have a 50 % risk of inheriting the mutation. From the genetics point of view, the disease is highly variable with respect to the specific gene mutation an...