Two antigens cross-reactive with carc inoembryonic antigen (CEA) and distinct from the nonspecif ic cross-react ing antigen were identified in meconium by double immunodiffusion with a conventional goat ant i -CEA antiserum. These two antigens together competi t ively inhibited cross-react ing antibodies against them in CEA radioimmunoassay and contr ibuted to the measurement of meconium CEA le...

Various anti-inflammatory drugs have been used for treatment of neonatal meconium aspiration syndrome (MAS). As their adverse effects are poorly described, this study compared effects of selective phosphodiesterase (PDE) 3 inhibitor olprinone and non-selective PDE inhibitor aminophylline on cardiovascular parameters in animal model of MAS. Oxygen-ventilated rabbits were intratracheally instille...

The features of fibrocystic disease of the pancreas are well recognized following the description by Andersen in 1938 of three main clinical forms. The first is that of intestinal obstruction in the first few days of life due to meconium ileus. About a fifth of all cases present with failure to pass meconium which is followed by vomiting and abdominal distension. It results from inspissation of...

conclusions despite the progress made in medicine, meconium aspiration syndrome is still one of the causes of newborn infants’ mortality. the mortality and morbidity rates can be reduced by improvement in perinatal care, prevention of post term delivery, timely caesarean and effective neonatal resuscitation at birth. results sixty-three newborn infants, diagnosed with meconium aspiration syndro...

Background: Previous studies have shown that meconium staining of the amniotic fluid may affect maternal and neonatal outcomes. In this study, we aimed to investigate the relationship between birth weight and meconium passage and its related factors in pregnant women.Materials and Methods: This matched case control study was conducted on a total of 200 newborns (100 as cases and 100 as controls...

In 2006, the American Academy of Pediatrics and the American Heart Association published the 2005 guidelines on neonatal resuscitation. Before the 2005 guidelines, management of a newborn with meconium-stained amniotic fluid included suctioning of the oropharynx and nasopharynx on the perineum after the delivery of the head but before the delivery of the shoulders. The 2005 guidelines did not s...