Alternative splicing, and specifically alternative exon inclusion, is one of the best studied mechanisms that create alternative isoforms. In its simplest form, alternative exon inclusion can be represented as exon skipping. Novel exon skipping events can be created through mutation events near and far from splice junctions, and thus may contribute to diseases, such as cancer. We systematically...

BACKGROUND Adolescence is an important period since the establishment of dietary pattern can also affect the adulthood. This study aimed to estimate the overall prevalence of skipping breakfast among Iranian students. METHODS The international and national databases, including Medline, Scopus, Science Direct, Embase, Web of sciences, Google Scholar, MagIran, and SID were searched 1945-2016 as...

Eating breakfast is important for the health and development of children and adolescents. This paper reports on the findings of an Australian survey of 699 thirteen-year-olds concerning the extent of skipping breakfast. Results indicated that approximately 12% of the sample skipped breakfast. Gender was the only statistically significant sociodemographic variable, with females skipping at over ...

PURPOSE Recurrent MET exon 14 splicing has been revealed in lung cancers and is a promising therapeutic target. Because we have limited knowledge about the natural history of MET mutant tumors, the current study was aiming to determine the clinical and pathological characteristics in non-small cell lung cancers (NSCLC). RESULTS Twenty-three patients (1.3%) were positive for MET exon 14 skippi...

In Drosophila, the Gal4-UAS system permits a transgene to be expressed in the same pattern as a gene of interest by placing the Gal4 transcription factor under control of the gene's DNA regulatory elements. If these regulatory elements are not known, however, expression of Gal4 in the desired pattern may be difficult or impossible. To solve this problem, we have developed a method for co-expres...

Removing commercials from television programs is a much sought-after feature for a personal video recorder. In this paper, we employ an unsupervised clustering scheme (CM Detect) to detect commercials in television programs. Each program is first divided into Ws-minute chunks, and we extract audio and visual features from each of these chunks. Next, we apply k-means clustering to assign each ch...

As an alternative to walking and running, humans are able to skip. However, adult humans avoid it. This fact seems to be related to the higher energetic costs associated with skipping. Still, children, some birds, lemurs and lizards use skipping gaits during daily locomotion. We combined experimental data on humans with numerical simulations to test whether stability and robustness motivate thi...

Adolescence is a grey area in the spectrum of life falling between childhood and adulthood. It an age transition when individual experiences rapid growth development, both physical psychological changes from being child to adult. School going period also increased vulnerability obesity, lack activity outdoor sports along with consumption fat-rich ‘junk’ foods, major cause obesity among affluent...

Food insecurity is a challenge in developing countries, especially the rural areas of Nigeria. It remains global and continues to be major public policy Nigeria other nations. Despite these, COVID-19 set posed serious threat food system security globally. This study, therefore, assessed level among farming households how they cope with situation during pandemic. Data for study were collected pr...