Together with an explosive growth of the mobile applications and emerging of cloud computing concept, mobile cloud computing (MCC) has been introduced to be a potential technology for mobile services. MCC integrates the cloud computing into the mobile environment and overcomes obstacles related to the performance (e.g., battery life, storage, and bandwidth), environment (e.g., heterogeneity, sc...

Merkel cell carcinoma (MCC) is a rare aggressive cutaneous malignancy of the elderly and immunocompromised populations. The clinical presentation of MCC is nonspecific, with the majority of cases presenting as localized skin involvement. Histologically and immunophenotypically, MCC is defined by both neuroendocrine and epithelial differentiation. Recently, the Merkel cell polyomavirus has been ...

Maximum Cross Correlation (MCC) technique have been used to derive coastal currents from sequential OCM derived suspended sediment concentration (SSC) maps and the MCC currents are integrated with the Ocean surface current analysis-Real time (OSCAR) ocean currents along the coastal regions of the Southern India. OSCAR currents are mainly depended on the oceanographic measurements from the satel...

Multiciliated cells (MCCs) differentiate hundreds of motile cilia that generate mechanical force required to drive fluid movement over epithelia [1, 2]. For example, metachronal beating of MCC cilia in the mammalian airways clears mucus that traps inhaled pathogens and pollutants. Consequently, abnormalities in MCC differentiation or ciliary motility have been linked to an expanding spectrum of...

The Monad Comprehension Calculus (MCC) is a highly expressive query language equal in expressive power to a subset of the Haskell programming language. This expressivity allows the MCC to subsume a variety of user-facing query languages, from nested relational algebra to OQL. The MCC possess a number of highlydesirable properties, including a normal form for queries that eliminates query nestin...

The articles in this issue address the high prevalence and substantial clinical burden of multiple chronic conditions (MCC) among adults. All of these papers further the goals outlined in the US Department of Health and Human Services (DHHS) MCC Strategic Framework (1,2). The article by Goodman, Posner, Huang, Parekh, and Koh (3) introduces the topic and describes the origin of the 20 condition...

Most research on adults with chronic conditions focuses on a single disease or condition, such as hypertension or diabetes, rather than on multiple chronic conditions (MCC). Our study's objective was to compare physician office visits by adults with MCC with visits by adults without MCC, by selected patient demographic characteristics. We also identified the most prevalent dyads and triads of c...

The mitotic (or spindle assembly) checkpoint system delays anaphase until all chromosomes are correctly attached to the mitotic spindle. When the checkpoint is active, a Mitotic Checkpoint Complex (MCC) assembles and inhibits the ubiquitin ligase AnaphasePromoting Complex/Cyclosome (APC/C). MCC is composed of the checkpoint proteins Mad2, BubR1, and Bub3 associated with the APC/C activator Cdc2...

UNLABELLED Escherichia coli microcin C (McC) consists of a ribosomally synthesized heptapeptide attached to a modified adenosine. McC is actively taken up by sensitive Escherichia coli strains through the YejABEF transporter. Inside the cell, McC is processed by aminopeptidases, which release nonhydrolyzable aminoacyl adenylate, an inhibitor of aspartyl-tRNA synthetase. McC is synthesized by th...

Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with an increasing incidence. The understanding of the molecular carcinogenesis of MCC is limited. Here, we scrutinized the PI3K/AKT pathway, one of the major pathways activated in human cancer, in MCC. Immunohistochemical analysis of 41 tumor tissues and 9 MCC cell lines revealed high levels of AKT phosphorylation at threonine 308 ...