67 Evaluation of Premature Mammary CASE PRESENTATION A nine year-old Quarter Horse pregnant mare (277 days in gestation) was presented to Department of Large Animals, the Koret School of Veterinary Medicine, the Hebrew University of Jerusalem, for evaluation of premature udder development and vaginal discharge. According to the owner, the mare was used as a pleasure riding horse, and was genera...

The mare is seasonally polyestrus, having an anovulatory period during the short light days of late fall and early winter, and beginning to ovulate as the days become longer during the winter. The complete estrus cycle is typically about 3 weeks, with 5 to 7 days of estrus and approximately 2 weeks of diestrus. When a mare lives within the natural social structure of the horse, i.e. a family ba...

BACKGROUND Vitamin-D-binding protein (VDBP) is a low molecular weight protein that is filtered through the glomerulus as a 25-(OH) vitamin D 3/VDBP complex. In the normal kidney VDBP is reabsorbed and catabolized by proximal tubule epithelial cells reducing the urinary excretion to trace amounts. Acute tubular injury is expected to result in urinary VDBP loss. The purpose of our study was to ex...

Enhancers and promoters assemble protein complexes that ultimately regulate the recruitment and activity of RNA polymerases. Previous work has shown that at least some enhancers form stable protein complexes, leading to the formation of enhanceosomes. We analyzed protein-DNA interactions in the murine β-globin gene locus using the methyltransferase accessibility protocol for individual template...

[1] A new magnetic map of the Moon, based on Lunar Prospector magnetometer observations, sheds light on the origin of the South Pole-Aitken basin (SPA), the largest and oldest of the recognized lunar basins. A set of WNW-trending linear to arcuate magnetic features, evident in both the radial and scalar observations, covers much of a 1000 km wide region centered on the NW portion of SPA. The so...

KREEP materials were thought to be last crystallized at the lunar crust and mantle boundary. Impact cratering and volcanism are mainly responsible for their distributions on the lunar surface. Therefore, observation of global KREEP materials and investigation of distributions in the areas of large basins are of critical importance to understand the geologic history of the Moon. Here we report t...

The mare exhibits nocturnal uterine contractions in the last 6 days of gestation. It is hypothesized that estradiol 17beta (O17beta) may be associated with the nightly increase in uterine contractions. The 24-h secretion pattern of plasma O17beta was measured in 3 pony mares in late gestation to identify changes in release as the mare neared parturition. Blood was collected weekly at 08:00 hour...

Origin of Lunar Basalts: A Geophysical Interpretation J. Arkani-Hamed Lunar Pyroclastic Soils of the Apollo 17 Double Drive Tube 74001/2 A. Basu, D. S. McKay, and S. J. Wentworth Lunar Explosive Volcanism: The Remote Sensing Perspective C. R. Coombs and B. R. Hawke The Optimal Lunar Resource: Ilmenite-rich Regional Pyroclastic Deposits C. R. Coombs, B. R. Hawke, and B. Clark Pyroclastic Volcani...

The mare ovary is unique in its anatomical structure; however, the signalling pathways responsible for physiological processes, such as follicular activation, remain uncharacterised. This provided us with the impetus to explore whether signalling molecules from important folliculogenesis pathways, phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and Janus kinase/signal transducer and activ...