BACKGROUND Cannabis use is common in patients with bipolar disorder, however little is known about cannabis as a risk factor for mania. In order to investigate the association between exposure to cannabis and subsequent development of manic symptoms whilst controlling for psychotic symptoms, a longitudinal population-based study was carried out. METHODS 4815 individuals aged 18 to 64 years we...

A case of Obsessive Compulsive Disorder with no contributory or past history who developed delusional mania while on clomipramine is presented. The manic symptoms resolved after discontinuation of drug. The link between serotonin and mania is speculated upon. The need to look for manic symptoms in patients on clomipramine is stressed.

BACKGROUND The bipolar spectrum disorders are considered an important and frequent psychiatric problem. The clinical complexity of these illnesses due to the coexistence of depressive and excitative phases is correlated with the global difficulty of adequate treatment; consequently, the prognosis is not optimal. For this reason, in recent years, novel nonpharmacologic physical approaches have b...

Fractal dimension of the electroencephalographic (EEG) signal has been argued to reflect the complexity of the underlying brain processes. To this date, conventional studies of EEG in mood disorders have not been able to distinguish between patients and normal individuals. Here we show that, compared to normal subjects, EEG fractal dimension is significantly augmented in the manic episode of bi...

Fractal dimension of the electroencephalographic (EEG) signal has been argued to reflect the complexity of the underlying brain processes. To this date, conventional studies of EEG in mood disorders have not been able to distinguish between patients and normal individuals. Here we show that, compared to normal subjects, EEG fractal dimension is significantly augmented in the manic episode of bi...