Signaling through the T cell antigen receptor leading to elimination (negative selection) or differentiation (positive selection) of developing thymocytes generates a self-tolerant T cell repertoire. Here we report that the serine-threonine kinase MINK selectively connects the T cell receptor to a signaling pathway that mediates negative but not positive selection. Analysis of this pathway sugg...

the current study aims to examine and identify competency dimensions, factors and indices for managers of science and technology parks of iranian public university in order to present of a conceptual model. the targeted population consisted of two parts including experts in the field and managers and experts in science and technology parks. for this purpose, exploratory method was used and data...

The rapid increase in the incidence of chronic non-communicable diseases over the past two decades cannot be explained solely by genetic and adult lifestyle factors. There is now considerable evidence that the fetal and early postnatal environment also strongly influences the risk of developing such diseases in later life. Human studies have shown that low birth weight is associated with an inc...

Objective: a fetus with a ring chromosome 20 is presented. Methods: at 16 weeks’ gestation, ultrasound examination evidenced no apparent structural malformation. Amniocentesis was performed for maternal anxiety. Results: chromosome analysis identified a ring chromosome 20 and array-CGH demonstrated that the ring including micro-deletion of the short arm in 20p13, that was extended for about 632...

To investigate the effect of surgical treatment of hydrosalpinx on the expressions of estrogen receptor (ER) and progesterone receptor (PR) in the endometrium in implantation window, a total of 60 patients with hydrosalpinx and 30 patients with fallopian tube obstruction were recruited. In the implantation window, immnohistochemistry was carried out to detect the expressions of ER and PR in the...

The specific aim of this academic study is to investigate the possible impacts of external and internal factors in the unique process of privatization on the changes of management accounting practices in listed companies of Tehran Stock Exchange which more than 51% of this companies' shares have been transferred to the private sector. For this purpose, a theoretical framework scientifically bas...