Transforming growth factor-beta (TGF-beta) suppresses tumor formation by blocking cell cycle progression and maintaining tissue homeostasis. In pancreatic carcinomas, this tumor suppressive activity is often lost by inactivation of the TGF-beta-signaling mediator, Smad4. We found that human pancreatic carcinoma cell lines that have undergone deletion of MADH4 constitutively expressed high endog...

the present study explored the effect of strategic human resources management on organizational performance with a mediating role of human capital in faculties of physical education and sport sciences of state universities of tehran. this research was descriptive-causal and the statistical population included all 166 staff and professors of faculties of physical education and sport sciences of ...

The abuse of novel psychoactive substances (NPS) has been increasing dramatically worldwide since late 2000s. By the end of 2015, more than 560 NPS had been reported to the European Monitoring Centre for Drugs and Drug Addiction. Although the most popular compounds are synthetic cannabinoids and psychostimulatory derivatives of cathinone (so-called β-keto-amphetamines), novel synthetic opioids ...

This study investigated factors predicting the courtship stalking behavior of male college students. Data were collected from 164 male college students who were described as men who wanted to date women who did not want to date them. Participants were from either a four-year university or a two-year college located in A-city, Korea. Courtship stalking behaviors were measured using Sinclair and ...

Background: Understanding the epidemiology of moderate-to-severe psoriasis is essential for its management. Objective: To assess the epidemiological characteristics of patients with moderate-to-severe psoriasis. Methods: Cross-sectional, observational epidemiological study conducted in Spain and Portugal. Data were collected by 332 dermatologists for 6 10 consecutive presenting patients. Result...