using complement fixation technique, serial serum samples from 15 patients undergoing surgical removal of malignant tumors were assayed for the presence of tumors antibodies against the cellular fractions of both normal and carcinomatous tissue. antibody responses against tumor associated antigens were detected in four cases. in all cases antibody activity was directed only against the supernat...

Ovaries are paired pelvic organs located on thesides of the uterus. Although it is rare in general population, between age group 20-40 years males,Testicular germ cell neoplasms most common form malignant tumour reported. In young women ovarian tumours rank second among tumors and males, testicular tumorsserves as leading percentage all seen early late adulthood (3rd 4th decade) life. The peopl...

The evolution of treatment for malignant ovarian germ cell tumors has been one the most successful in history gynecologic oncology, with dysgerminoma as common type tumors. Since introduction platinum-based chemotherapy 1980s, 5-year survival rates early-stage dysgerminomas have close to 100%, and high 98% advanced stages. Despite this remarkable achievement, many questions remain routine treat...

We report the cytogenetic analysis of 124 adult male germ cell tumors ascertained consecutively at the Memorial Sloan-Kettering Cancer Center between 1988 and 1990. Biopsies from testicular and extragonadal primary and metastatic lesions studied included all histological subtypes of germ cell tumors and cases of malignant transformation. Nonrandom numerical and structural chromosomal abnormalit...

Germ cell tumors make up 15% to 20% of all ovarian tumors, 95% of which are dermoid cysts, also known as benign cystic teratomas. Primarily ectodermally derived, tissues can grow from any of the germ cell layers. Tumors occur bilaterally in 10% of cases, and there appears to be an increased rate of sterility in patients with cystic teratomas. These tumors are found in women of reproductive age,...

A female's risk at birth of having ovarian tumor sometime in her life is 6-7%. Relative frequency of ovarian tumor is different for western and Asian countries. Two third of ovarian tumors occur in women of reproductive age group. This study was done in Tribhuvan University Teaching Hospital with aim to find out frequency of different histological types of ovarian tumors and their age distribut...

OBJECTIVE To find out the mode of presentation, age distribution and the prevalence of various histological subtypes of testicular tumors. METHOD All consecutive cases of testicular tumors diagnosed in the department of pathology, the Aga Khan University Hospital, Karachi, during the period of eight years (1991-98) were included in this study. Relevant clinical details such as age, clinical p...

metallothionein (mt) manifests varying expression levels in carcinomas, and they may be considered as valuable cell cancerization biomarkers for diagnosis of patients with cancers. a meta-analysis was conducted to evaluate comprehensively the mt expression difference in various benign tumors and malignant tumors, which compared the high with low mt expression levels in patients of the available...

Endometrial carcinoma with a germ cell tumor component is a rare event. Here we report a uterine neoplasm with a unique combination of endometrioid adenocarcinoma and mixed germ cell malignant elements. A 28-year-old woman with abnormal vaginal bleeding, an abdominal mass, and elevated alfa-fetoprotein and beta-human chorionic gonadotropin (β-hCG) levels had a history of biopsy of an omental ma...