نتایج جستجو برای: malignant meningioma m0337826

تعداد نتایج: 216991  

Journal: :International journal of oncology 2006
Shakuntala Kondraganti Christopher S Gondi Ian McCutcheon Dzung H Dinh Meena Gujrati Jasti S Rao William C Olivero

In recent years, RNA interference (RNAi) has emerged as an effective method to target specific genes for silencing. Several groups are actively exploring the use of small interfering RNA (siRNA) for therapeutic applications to treat cancer. Our previous studies have demonstrated the inhibition of various proteases, including serine proteases, cysteine proteases and matrix metalloproteases, via ...

Journal: :Neurosurgical focus 2011
Winward Choy Won Kim Daniel Nagasawa Stephanie Stramotas Andrew Yew Quinton Gopen Andrew T Parsa Isaac Yang

Meningiomas are mostly benign, slow-growing tumors of the CNS that originate from arachnoidal cap cells. While monosomy 22 is the most frequent genetic abnormality found in meningiomas, a multitude of other aberrant chromosomal alterations, signaling pathways, and growth factors have been implicated in its pathogenesis. Losses on 22q12.2, a region encoding the tumor suppressor gene merlin, repr...

Journal: :Cancer research 2005
Ileana C Cuevas Alison L Slocum Peter Jun Joseph F Costello Andrew W Bollen Gregory J Riggins Michael W McDermott Anita Lal

Meningiomas constitute the second most common central nervous system tumor, and yet relatively little is known about the molecular events that are important for the pathogenesis and malignant progression of these tumors. We have used serial analysis of gene expression to compare the transcriptomes of nonneoplastic meninges and meningiomas of all malignancy grades. A novel finding from this scre...

Journal: :Clinics 2005
Tobias Alécio Mattei Josias Alécio Mattei Ricardo Ramina Paulo Henrique Aguiar José Pindaro Plese Raul Marino

PURPOSE In recent years there have been many attempts to define a subset of aggressive malignant meningiomas based on histopathology and imaging technologies. The purpose of this study was to evaluate the level of peritumoral edema and its volume using the imaging technologies, computer tomography and magnetic resonance imaging, and correlate these results with the histological WHO classificati...

2013
Payam Moein Omid Behnamfar Nima Khalighinejad Ziba Farajzadegan Salman Abbasi Fard Mostafa Razavi Parvin Mahzouni

BACKGROUND Although primary spinal cord tumors (PSCTs) comprise a minority of primary central nervous system tumors, they often impose a great deal of morbidity on their victims. Few epidemiologic studies have addressed PSCTs in Iran. MATERIALS AND METHODS We analyzed the demographic/clinical features of all primary intraspinal tumors (with a specific focus on primary intradural spinal cord t...

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