Sexual motivation and copulation in male rats are associated with dopamine release in the nucleus accumbens. Demasculinized copulatory behavior has been demonstrated in prenatally stressed adult male rats. We have previously reported that approximately 80% of prenatally stressed male rats do not exhibit copulation and that no significant changes in nucleus accumbens dopamine release are seen du...

OBJECTIVE In this study we investigated the effects of spearmint (Mentha spicata Labiatae) on the reproductive system, fertility and number of offspring in adult male rats. MATERIALS AND METHODS Adult Wistar male rats in one control (C) and three experimental groups (I, II and III) received 0, 10, 20 and 40 mg/kg spearmint extract orally for 45 days, respectively. Following this treatment, th...

The toxicities of ethylene glycol (EG) and ethylene glycol monoethyl ether (EGEE) were studied in Fischer 344/N rats and B6C3F1 mice. In a 13-week study, EG was administered in feed to groups of 10 rats and 10 mice of both sexes at dose levels of 0 (control), 0.32, 0.63, 1.25, 2.5 and 5.0%. Kidney/body weight ratios were elevated in the 2.5 and 5.0% dose groups of male and female rats relative ...

In young (4-week-old) male and female spontaneously hypertensive (SH) rats, ethanol metabolic rate in vivo and hepatic alcohol dehydrogenase activity in vitro are high and not different in the two sexes. In males, ethanol metabolic rate falls markedly between 4 and 10 weeks of age, which coincides with the time of development of sexual maturity in the rat. Alcohol dehydrogenase activity is also...

Kersen parasite leaves (Dendropthoe pentandra (L.) Miq) is a type of that hemiparasite and contains active compounds, namely, flavonoids, terpenoids tannins. This compound has benefits as an antihyperglycemic. The aim this study to determine the effect lowering blood glucose levels from infusion (Dendrophthoe in white male rats induced by alloxan. research was laboratory experimental with rando...

Acute pancreatitis (AP) is a common serious stirring disease of the pancreas characterized by strict abdominal twinge that lasts for days to weeks. Rats were injected with high dose amino acid L-arginine (500 mg/kg B.W.). The study has been done induce acute L-Arginine (Arg) and investigate effect AP on body weight, weight gain, serum amylase, lipase, oxidative stress proinflammatory cytokine p...

Reductions in testicular mass, sperm motility, and mating frequency have been attributed to the stresses caused by confinement of Sprague-Dawley male rats in nose-only inhalation exposure tubes. Testicular changes, including an increase in testicular atrophy, have been detected at an increased incidence in male rats used in inhalation studies as compared with rats of the same age and strain use...

objectives: the purpose of current study was to determine the effect of phaleria macrocarpa (p. macrocarpa)fruits aqueous extract on reproductive performance of adult male rats by assessing the serum testosterone level and evaluating their libido behavior. methods and materials: eighteen male adult spraque dawley rats were divided into three groups and designated as treatment (240 mg/kg p. macr...

objective: opioid consumption has been widely increasing across the globe; however, it can cause adverse effects on the body. morphine, an opioid, can reduce sex hormones and fertility. withania somnifera (ws) is a traditional herb used to improve sexual activities. this study strives to investigate the effect of ws on sex hormones and gonadotropins in addicted male rats. materials and methods:...

background: epilepsy is a chief communal health problem. antiepileptic drugs only provide symptomatic treatment. walnut kernels (wk) have high concentrations of phenolic compounds, which have beneficial effects on human health because of their antioxidant and anti-atherogenic properties. the present study was designed to evaluate the efficacy of wk supplementation for the prevention of experime...