نتایج جستجو برای: malassezia globosa

تعداد نتایج: 1498  

B Tarazooei F Nayeri H Zeraati K Zomorodian N Jalali Zand P Kord Bacheh S Zomorodian SH Mir Hendi SM Milani

Background and aim: Malassezia yeasts are normal flora of humans and warm-blooded animals. These lipophilic yeasts are associated with skin diseases in neonates such as pityriasis versicolor, neonatal postulitis and seborrheic or atopic dermatitis. Moreover in the recent years, these yeasts are increasingly isolated form fatal catheter-related fungemia in premature neonates. Concerning th...

Journal: :Environmental Microbiology 2008
Michael Y Galperin

The end of 2007 brought us draft genome sequences of two eukaryotic microorganisms, Babesia bovis and Malassezia globosa, as well as complete genomes of the ammonia-oxidizing archaeal chemoautotroph Nitrosopumilus maritimus, and several environmental bacteria (Table 1). In terms of genome size, this list covers both sides of the spectrum: the 245 kb genome of an obligate insect symbiont Sulcia ...

Journal: :Medical mycology 2010
Filippo de Bellis Gemma Castellá F Javier Cabañes Ross Bond

Malassezia nana is a recently-described lipophilic yeast that has been isolated from the ear canals and skin of cats in Japan and Europe and from Brazilian cattle with or without otitis externa. Previous reports have demonstrated that significant intra-species variability exists in the DNA sequence of the intergenic spacer 1 region (IGS1), particularly amongst M. globosa, M. restricta and M. pa...

2016
Andrew G. S. Warrilow Claire L. Price Josie E. Parker Nicola J. Rolley Christopher J. Smyrniotis David D. Hughes Vera Thoss W. David Nes Diane E. Kelly Theodore R. Holman Steven L. Kelly

Malassezia globosa cytochromes P450 CYP51 and CYP5218 are sterol 14α-demethylase (the target of azole antifungals) and a putative fatty acid metabolism protein (and a potential azole drug target), respectively. Lanosterol, eburicol and obtusifoliol bound to CYP51 with Kd values of 32, 23 and 28 μM, respectively, catalyzing sterol 14α-demethylation with respective turnover numbers of 1.7 min(-1)...

Journal: :Antimicrobial agents and chemotherapy 2011
Nancy L Reeder Jerry Kaplan Jun Xu R Scott Youngquist Jared Wallace Ping Hu Kenton D Juhlin James R Schwartz Raymond A Grant Angela Fieno Suzanne Nemeth Tim Reichling Jay P Tiesman Tim Mills Mark Steinke Shuo L Wang Charles W Saunders

Zinc pyrithione (ZPT) is an antimicrobial material with widespread use in antidandruff shampoos and antifouling paints. Despite decades of commercial use, there is little understanding of its antimicrobial mechanism of action. We used a combination of genome-wide approaches (yeast deletion mutants and microarrays) and traditional methods (gene constructs and atomic emission) to characterize the...

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