The histologic appearance of a consecutive series of 200 neovascular membranes was analyzed. Specific angiographic manifestations of exudative age-related macular degeneration such as classic or occult choroidal neovascularization, vascularized pigment epithelial detachment, tear of the retinal pigment epithelium, polypoidal choroidal vasculopathy and deep retinal vascular anomalous complex cor...

Purpose The purpose of this study was to evaluate the impact of supplemental macular carotenoids (including versus not including meso-zeaxanthin) in combination with coantioxidants on visual function in patients with nonadvanced age-related macular degeneration. Methods In this study, 121 participants were randomly assigned to group 1 (Age-Related Eye Disease Study 2 formulation with a low do...

Central serous chorioretinopathy (CSCR) is one of several retinal disorders that may cause visual loss. It characterized by detachment the neurosensory retina, often associated with focal detachments an altered pigment epithelium, mostly confined to macular area. As CSCR considered be correlated increased level testosterone, it was interest if also linked occurrence polycystic ovary syndrome (P...

PURPOSE To report the long-term (>5 years) results of full macular translocation in patients with choroidal neovascularization (CNV). DESIGN Retrospective, interventional case series. METHODS This study involved 32 eyes of 32 patients who had undergone full macular translocation for CNV. The median follow-up was 6.5 years (range, 5.2 to 7.7 years). We evaluated the best-corrected visual acu...

BACKGROUND The pathogenesis of macular hole formation is widely accepted as a tractional force at the vitreo-retinal interface in fovea. We report a case of macular hole after intravitreous aflibercept injection for age-related macular degeneration (AMD) associated with contraction of the retinal pigment epithelium (RPE) at the edge of a fibrovascular pigment epithelial detachment (PED). CASE...

Human retinal macular pigment (MP) is formed by the carotenoids lutein and zeaxanthin (including the isomer meso-zeaxanthin). MP has several functions in improving visual performance and protecting against the damaging effects of light, and MP levels are used as a proxy for macular health-specifically, to predict the likelihood of developing age-related macular degeneration. While the roles of ...

Background Lutein and zeaxanthin are carotenoids that are selectively taken up into the macula of the eye, where they may protect against development of age-related macular degeneration (AMD). Past studies have reported an agedependent decline of macular pigment optical density (MPOD) in patients with AMD. In the present study we investigated the age-dependence of MPOD and melatonin using spect...