نتایج جستجو برای: macrophage chemotactic protein
تعداد نتایج: 1276781 فیلتر نتایج به سال:
Monocyte chemotactic factors released from type II pneumocyte-like cells in response to TNF-a and IL-1a. S. Koyama, E. Sato, H. Nomura, K. Kubo, M. Miura, T. Yamashita, S. Nagai, T. Izumi. #ERS Journals Ltd 1999. ABSTRACT: It has been reported that tumour necrosis factor (TNF)-a and interleukin (IL)-1 induce the release of monocyte chemotactic factors (MCF), including chemokines, from A549 cell...
The cellular infiltrates of certain inflammatory processes found in parasitic infection or in allergic diseases consist predominantly of eosinophilic granulocytes, often in association with activated T cells. This suggests the existence of chemotactic agonists specific for eosinophils and lymphocyte subsets devoid of neutrophil-activating properties. We therefore examined four members of the in...
Lumbar Modic change (MC) can serve as a diagnostic marker well an independent source of chronic low back pain (CLBP). This study aimed to test for the existence serum biomarkers in CLBP patients with MC. Age- and sex-matched confirmed MC on lumbar MRI (n = 40) pain-free controls were assessed. was classified into M1, predominating M2 M2. volumes calculated. Fasting blood samples assessed inflam...
Lymphocyte trafficking is an essential process in immune and inflammatory functions which can be thought to contain at least two main components: adhesion and migration. Whereas adhesion molecules such as the selections are known to mediate the homing of leukocytes from the blood to the endothelium, the chemoattractant substances responsible for the migration of specific subsets of lymphocytes ...
The recently discovered CC chemokine, regakine-1, is constitutively present in bovine serum and synergizes with the CXC chemokine interleukin-8 (IL-8) to chemoattract neutrophils. Here we show that regakine-1 cooperates with the CXC chemokine receptor 2 ligand neutrophil activating protein-2 (NAP-2) and the anaphylatoxin C5a, two other mediators of inflammation present in the circulation. Neutr...
Background: H pylori is a human gastric pathogen. Chemotaxis is an essential factor in colonization of H pylori, but very little is known about its chemotactic responses at different pH conditions, especially in acidic environment of stomach as its natural habitant. Methods: We first determined survival of H pylori under various pH conditions in the presence and absence of urea. Chemotaxis was...
Smoke extract stimulates lung fibroblasts to release neutrophil and monocyte chemotactic activities.
Accumulation of monocytes and neutrophils and fibrous distortion of the airway are characteristics of airway disease secondary to smoking. The presence of inflammatory cells and fibrosis correlate, and, therefore, we postulated that lung fibroblasts might release chemotactic activity for neutrophils and monocytes in response to smoke extract. To test this hypothesis, human fetal lung (HFL1) fib...
In human obesity, the stroma vascular fraction (SVF) of white adipose tissue (WAT) is enriched in macrophages. These cells may contribute to low-grade inflammation and to its metabolic complications. Little is known about the effect of weight loss on macrophages and genes involved in macrophage attraction. We examined subcutaneous WAT (scWAT) of 7 lean and 17 morbidly obese subjects before and ...
Adipose tissue insulin resistance (Adipo-IR) results in excessive release of free fatty acids from adipose tissue, which plays a key role in the development of "lipotoxicity." Therefore, amelioration of Adipo-IR may benefit the treatment of other metabolic abnormalities. Here we found that treatment with the alcoholic extract of ginger (50 mg/kg/day, by oral gavage) for five weeks attenuated li...
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