نتایج جستجو برای: m2 gene

تعداد نتایج: 1181315  

Journal: :Journal of High Energy Physics 2022

A bstract We present a family of new M2-brane solutions in AdS 7 × S 4 that calculate toroidal BPS surface operators the $$ \mathcal{N} N = (2 , 0) theory. These observables are conformally invariant and not subject to anomalies so we able evaluate their finite expectation values at leading order large N . In...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1991
M Blum A Demierre D M Grant M Heim U A Meyer

The acetylation polymorphism is one of the most common genetic variations in the transformation of drugs and chemicals. More than 50% of individuals in Caucasian populations are homozygous for a recessive trait and are of the "slow acetylator" phenotype. They are less efficient than "rapid acetylators" in the metabolism of numerous drugs and environmental and industrial chemicals. The acetylati...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Kazumi Uchida Sylke Schneider Ji Min Yochim Hidekazu Kuramochi Kazuhiko Hayashi Ken Takasaki Dongyun Yang Kathleen D Danenberg Peter V Danenberg

PURPOSE Cyclooxygenase-2 (COX-2) is generally elevated in tumors compared with normal tissue and apparently has an important role in tumor development. A number of studies have found high expression of COX-2 to be an unfavorable prognostic factor for overall survival in several cancers. However, the influence of COX-2 expression levels on tumor response to chemotherapy has been relatively littl...

Journal: :The EMBO journal 1999
L J Otero M P Ashe A B Sachs

Translation initiation in extracts from Saccharomyces cerevisiae involves the concerted action of the cap-binding protein eIF4E and the poly(A) tail-binding protein Pab1p. These two proteins bind to translation initiation factor eIF4G and are needed for the translation of capped or polyadenylated mRNA, respectively. Together, these proteins synergistically activate the translation of a capped a...

Journal: :Blood 2006
Gholamreza Hassanzadeh Ghassabeh Patrick De Baetselier Lea Brys Wim Noël Jo A Van Ginderachter Sofie Meerschaut Alain Beschin Frank Brombacher Geert Raes

Compared with type I cytokine-associated myeloid (M1) cells, the molecular repertoire and mechanisms underlying functional properties of type II cytokine-associated myeloid (M2) cells are poorly characterized. Moreover, most studies have been limited to in vitro-elicited M2 cells. Here, comparative gene expression profiling of M1 and M2 cells, elicited in murine models of parasitic infections a...

Journal: :The Journal of biological chemistry 1986
T Noguchi H Inoue T Tanaka

The complete nucleotide sequences of rat M1- and M2-type pyruvate kinase mRNAs were determined by sequencing the cDNAs and by analyses of S1 nuclease mapping and primer extension. The sequences have an identical molecular size of about 2220 nucleotides excluding a poly(A) tail and include 1593-nucleotide coding region. Their nucleotide sequences are identical except for 160-nucleotide sequences...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2006
Myong Suk Ko Seung Jin Lee Jin Wan Kim Jee Woong Lim Sang Geon Kim

Comprehensive mechanistic studies suggest that oltipraz exerts cancer chemopreventive effects through the induction of glutathione S-transferase (GST). Previously, we have shown that the activation of CCAAT/enhancer binding protein-beta (C/EBPbeta), promoted by oltipraz, contributes to the transcriptional induction of the GSTA2 gene. Studies also indicated that exposure of animals to oltipraz t...

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