In the present study, the hydrophobicity of a 26-residuea-helical peptide (peptideP)was altered to study the effects of peptide hydrophobicity on the mechanism of action of cationic anticancer peptides. Hydrophobicity of the nonpolar face of the peptideswas shown to correlate with peptide helicity. The self-association ability of peptides in aqueous environment, determined by the reversed-phase...

Water confined between adjoining hydrophobic and hydrophilic surfaces (a Janus interface) is found to form stable films of nanometer thickness whose responses to shear deformations are extraordinarily noisy. The power spectrum of this noise is quantified. In addition, the frequency dependence of the complex shear modulus is a power law with slope one-half, indicating a distribution of relaxatio...

Kinetic hydrophobic measurements were performed by confronting 40 mutans streptococci from thirty 10- to 20-year-old patients with 200 ml hexadecane (Sigma). Fourteen patients had high dental caries risk (Group A), dmft + DMFT > 5 with 3 or more active caries, and 16 had low dental caries risk (Group B), dmft + DMFT < 3 without active caries. Twenty bacteria from Group A and 20 bacteria from Gr...

We study the statistical properties of hydrophobic/polar model sequences with unique native states on the square lattice. It is shown that this ensemble of sequences differs from random sequences in significant ways in terms of both the distribution of hydrophobicity along the chains and total hydrophobicity. Whenever statistically feasible, the analogous calculations are performed for a set of...

We study the statistical properties of hydrophobic/polar model sequences with unique native states on the square lattice. It is shown that this ensemble of sequences differs from random sequences in signiicant ways in terms of both the distribution of hydrophobicity along the chains and total hydrophobicity. Whenever statistically feasible, the analogous calculations are performed for a set of ...

Objectives To determine the effect of root canal irrigants on the hydrophobicity and adherence of Staphylococcus epidermidis (S. epidermidis) to root canal dentin in vitro. Materials and Methods Root dentin blocks (n = 60) were randomly divided into 4 groups based on the irrigation regimen: group 1, saline; group 2, 5.25% sodium hypochlorite (NaOCl); group 3, 5.25% NaOCl followed by 17% ethyl...

Zinc oxide nano-particles with the average diameter of about 25 nm were modified with different mole ratios of trimetoxyvinyl silane (TMVS) and oleic acid, as coupling agents, in order to modify their surface properties and render them more hydrophobic. Then, dispersibility of the surface modified nano-particles was examined in some monomers with different levels of hydrophobicity, including me...

Variations on hydrophobicity were monitored in two marine obligate hydrocarbonoclastic bacteria: Alcanivorax borkumensis SK2T and Thalassolituus oleivoras MIL-1T. These strains were inoculated, separately in ONR7a mineral medium with different concentration of sodium acetate. During 10 days measurements of cellular abundance and cellular hydrophobicity (capacity to adhere at polystyrene) were c...

A fundamental understanding of attachment of surface-coated nanoparticles (NPs) is essential to predict the distribution and potential risks of NPs in the environment. Column deposition studies were used to examine the effect of surface-coating hydrophobicity on NP attachment to collector surfaces in mixtures with varying ratios of octadecylichlorosilane (OTS)-coated (hydrophobic) glass beads a...

We explored the influence of the hydrophilic-hydrophobic balance of a series of natural bile acids on cholesterol absorption in the mouse. Male C57L/J mice were fed standard chow or chow supplemented with 0.5% cholic; chenodeoxycholic; deoxycholic; dehydrocholic; hyocholic; hyodeoxycholic; alpha-, beta-, or omega-muricholic; ursocholic; or ursodeoxycholic acids for 7 days. Biliary bile salts we...