نتایج جستجو برای: lymphoide dendritic cell
تعداد نتایج: 1709577 فیلتر نتایج به سال:
(Immunity 53, 759–774.e1–e9; October 13, 2020) In the originally published article, authors used chromatin immunoprecipitation sequencing (ChIP-seq) data for IRF4 to identify binding sites in cDC2 comparison with IRF8 cDC1. However, due an oversight during manuscript preparation, they did not upload ChIP-seq GEO repository. This has now been uploaded and available set GSE174011. The apologize a...
Dendritic cells are potent antigen-presenting cells endowed with the unique ability to prime T-cell responses. To present foreign antigens to na ive T cells, dendritic cells must migrate from inflamed or injured peripheral tissues to the closest draining lymph nodes through afferent lymphatic vessels. In addition, conventional dendritic cells, plasmacytoid dendritic cells and monocytes enter ly...
OBJECTIVE Although dendritic cells are known to play a role in atherosclerosis, few studies have examined the contribution of the wide variety of dendritic cell subsets. Accordingly, their roles in atherogenesis remain largely unknown. We investigated the ability of different dendritic cell subsets to become foam cells after contact with aggregated low-density lipoprotein (LDL; the predominant ...
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To directly dissect the role of each immune component in human tumor immunopathogenesis, we have studied the interaction between dendritic cells and T cells in the tumor environment of patients with ovarian carcinoma. We previously reported that functional plasmacytoid dendritic cells, but not functionally mature myeloid dendritic cells, accumulated in tumor microenvironments. We now show that ...
OBJECTIVE Immune-mediated destruction of beta-cells resulting in type 1 diabetes involves activation of proinflammatory, islet autoreactive T-cells, a process under the control of dendritic cells of the innate immune system. We tested the hypothesis that type 1 diabetes development is associated with disturbance of blood dendritic cell subsets that could enhance islet-specific autoimmunity. R...
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