In an experimental study, the morphofunctional features of spleen 6-month-old white rats were studied in normal conditions and chronic radiation sickness. The study found that response to action a factor rats, there is decrease structural parameters. This reflected morphological parameters organ. As result, functional activity spleen’s lymphoid tissue decreases.

An 11 year – old mixed female Labrador was presented with two masses in trunk and neck. The tumoral masses were excised and sent for histopathological and immunohistochemical analyses. Histopathological examination of masses revealed diffuse infiltration of small sized lymphoid cells in subcutaneous tissue which were intense around the blood vessels. More than 10% lymphoid cells were CD3 positi...

Background: The appendix is considered as part of the gut-associated lymphoid tissue; however, lymphocyte subsets in this tissue are not fully defined. Objective: To investigate and compare the function and phenotype of lymphocyte subsets in peripheral blood and appendix of patients with normal and inflamed appendix tissues. Methods: Peripheral blood samples and appendiceal mononuclear cells we...

Lymphoid tissue-inducer cells are hematopoietic cells essential for the organogenesis of several lymphoid structures during both fetal and adult life, whereas natural killer cells are key effector lymphocytes of the innate immune system. A series of recent reports has identified RORγt(+)NKp46(+) interleukin-22-producing cells in gut and tonsils that share features with both lymphoid tissue-indu...