نتایج جستجو برای: lymphocytic

تعداد نتایج: 38597  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 1997
T C Meeker L T Lay J M Wroblewski F Turturro Z Li P Seth

We have hypothesized that adenoviral vectors might mediate gene transfer into cell lines derived from human lymphocytic malignancies, such as lymphoma, lymphocytic leukemia, and myeloma. A panel of 33 cell lines was studied for their ability to be transduced by an adenoviral (AD) vector encoding the Escherichia coli beta-galactosidase gene (AD-betagal). A cytochemical assay and a flow cytometry...

2017
Lucas A. Heldt Manica Philip R. Cohen

Chronic lymphocytic leukemia is a lymphoproliferative disorder characterized by a gradual accumulation of neoplastic B-lymphocytes. Ibrutinib is a novel therapy for chronic lymphocytic leukemia. Ibrutinib therapy has been associated with nail plate abnormalities. Other common cutaneous adverse events caused by ibrutinib appear to be bruising, hair changes, pruritus, and rashes. We describe the ...

2018
Claudia Dürr Bola S. Hanna Angela Schulz Fabienne Lucas Manuela Zucknick Axel Benner Andrew Clear Sibylle Ohl Selcen Öztürk Thorsten Zenz Stephan Stilgenbauer Min Li-Weber Peter H. Krammer John G. Gribben Peter Lichter Martina Seiffert

Chronic lymphocytic leukemia is a malignancy of mature B cells that strongly depend on microenvironmental factors, and their deprivation has been identified as a promising treatment approach for this incurable disease. Cytokine array screening of 247 chronic lymphocytic leukemia serum samples revealed elevated levels of tumor necrosis factor (TNF) receptor-1 which were associated with poor clin...

Journal: :International journal of clinical and experimental pathology 2008
Carlos A Rubio Edward J Dick Abiel Orrego Gene B Hubbard

We previously reported in humans a novel histologic phenotype of non-gastro-esophageal reflux disease called lymphocytic esophagitis. In this work, the esophagi of 121 non-human primates (103 baboons and 18 macaques) were investigated. 45 baboons (43.7%) and 9 macaques (50%) had lymphocytic esophagitis. The lymphocytic infiltration in the squamous epithelium involved not only papillary but also...

2017
Elissandra Machado Arlindo Natália Aydos Marcondes Flavo Beno Fernandes Gustavo Adolpho Moreira Faulhaber

BACKGROUND Distinction between mature B-cell neoplasms can be difficult due to overlapping of immunologic features and clinical manifestations. This study investigated whether quantifying mean fluorescence intensity of four monoclonal antibodies in a flow cytometry panel is useful for the differential diagnosis and characterization of these disorders. METHODS The expressions of CD52, CD200, C...

Journal: :Haematologica 1999
M Carrasco A Remacha A Sureda P Sardà R Martino J Sierra

1. Caballero MD, Gonzalez M, Canizo MC, Orfao A, Nieto MJ, San-Miguel JF. Concomitant chronic lymphocytic leukemia (CLL) and acute myeloid leukemia. Complete remission of CLL achieved with high-dose cytosine arabinoside. Leukemia 1992; 6:856-8. 2. Conlan MG, Mosher DF. Concomitant chronic lymphocytic leukemia, acute myeloid leukemia, and thrombosis with protein C deficiency. Case report and rev...

Journal: :Chest 1997
S Jouveshomme L J Couderc F Ferchal D Vignon B Autran E Balloul I Caubarrere

Herein is a report of an adult case of primary HIV infection with cytomegalovirus coinfection causing cough, fever, and lymphocytic alveolitis. Primary HIV infection has not been previously reported as a cause of lymphocytic alveolitis.

Journal: :European journal of endocrinology 2006
Angelika Gutenberg Volkmar Hans Maximilian J A Puchner Jürgen Kreutzer Wolfgang Brück Patrizio Caturegli Michael Buchfelder

OBJECTIVE Primary hypophysitis comprises of three distinct histomorphological entities: lymphocytic, granulomatous and xanthomatous. Clinical features of the three subtypes for diagnostic and treatment strategies have yet not been well characterized. METHODS Endocrine function, visual fields and acuity as well as magnetic resonance imaging characteristics were assessed before and after transp...

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