Background and aim: Papillary thyroid carcinoma (PTC), unlike other cancers, is completely curable if the treatment begins at early stages of the disease, before any metastasis occurs. One of the common places that the cancer may invade is the cervical lymph node. On this basis, many surgeons suggest prophylactic central cervical lymph nodes dissection in such patients, but others do not agree ...

Background: It is well known that, at the time of the initial presentation of patients with non-small cell lung cancer, N-status is very important in accurate staging and avoiding inappropriate surgical procedures. Also, if mediastinal lymph node metastasis (N2) of non-small cell lung cancer (stage IIIA) is present, neoadjuvant (preoperative) chemora-diotherapy is indicated therefore a quick an...

Introduction: HER-2 is a protein receptor of growth. Approximately 25% of breast cancers have overexpress HER-2. This study was designed to determine frequency of HER-2 overexpression in patients with breast cancer. Additionally, it intended to explore its relationship with some variables such as age, histopathologic diagnosis,tumor size, axillary lymph node involvement. Methods: This analyti...

Background & Aims: Due to the high incidence of breast cancer, the use of easy, safe, noninvasive and readily available diagnostic procedures that can accurately determine the initial stages of the disease and its spread is very important. Ultrasonography as a method may be able to realize these goals and to help patients and physicians. The aim of this study was to evaluate diagnostic val...

Background: Breast cancer is the most common female malignancy world wide and in Iran as well and is  the second cause of death due to malignancy after lung cancer. Varieties of factors such as estrogen and progesterone receptors, and axillary lymph node involvement may influence the prognosis and therapeutic  approach. However, mutation in HER2 gene may also affect the prognosis. In this study...

Background and Objective: Thyroid cancer is the most common endocrine malignancy. The most common well-differentiated form of thyroid cancer is papillary carcinoma (PTC). Few studies on determining the role of CD10 in PTC prognosis have been performed, furthermore they have been controversial. This study was designed to determine the correlation of CD10 expression with age, gender, tumor size, ...