a 60-year-old patient with testicular seminoma was referred for f-18 fdg pet/ct study to evaluate recurrence. in addition to hypermetabolic cervical, mediastinal and hilar lymph node tumoral metastases, segmental intense fdg uptake along the lumbar spinal cord suggestive of tumoral metastasis was noted which quite an unusual presentation is.  at the time of pet study the patient was symptomless...

BACKGROUND Intralymphatic tumors in the extratumoral area are considered to represent the preceding phase of lymph node metastasis. The aim of this study was to clarify the biological properties of intralymphatic tumors susceptible to the development of lymph node metastasis, with special reference to the expression of cancer initiating/stem cell (CIC/CSC) related markers in cancer cells and th...

background: the lysosomal protease cathepsin d (cd) has been associated with tumor progression in malignant tumors including oral squamous cell carcinoma (oscc). the purpose of this study was to find out any association between the cd and lymph node metastasis and to study the correlation of cd with various clinicopathological parameters to aid in assessment of its role as a prognostic indicato...

In this article, Table 1 has been published in a confusing layout. We would like to clarify that the table should look as follows: Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. Table 1 Tumour-node-metastasis (TNM)...

Classical lymphadenopathies, such as Virchow's node (left supraclavicular lymph node metastasis) and Irish node (left axillary lymph node metastasis), are important findings that may indicate the presence of gastric cancer and other gastrointestinal malignancies.

Background. Gastric cancer (GC) is an important malignant disease around the world. Abnormalities of microRNAs (miRNAs) have been implicated in carcinogenesis of various cancers. In the present study, we examined miR-21 expression in human gastric cancer with lymph node metastasis and attempted to uncover its relationship with clinicopathologic data, especially with lymph node metastasis. Mater...

BACKGROUND To determine the prognostic relevance of neuroendocrine differentiation in poorly differentiated colorectal cancer. METHODS The clinicopathological features and survival of 70 patients with poorly differentiated colorectal cancer were analyzed retrospectively. Chromogranin A and synaptophysin were used as neuroendocrine markers. Patients were followed-up for more than 3 years or un...

BACKGROUND For patients with papillary thyroid carcinoma (PTC), lymph node metastasis is associated with an increased recurrence rate. The purpose of this study was to investigate whether the vascular endothelial growth factor (VEGF), microvessel density (MVD), and vascular index (VI) can predict lymph node metastasis in patients with PTC. METHODS From January 2011 to October 2011, 202 patien...

Lymph node metastasis of rectal cancer in different stages had incidences of T1 11.9%, T2 25.7%, T3 55.9%, and T4 62.4% in a study of 6,442 patients in multiple centers in Japan (Watanabe et al., 2012). Thus, the incidence of lymph node metastasis of rectal cancer was very high in stage T3 and higher. Lymph node metastasis is a risk factor for local recurrence and a poor prognosis in rectal can...