wnloade pose: Atu027, a novel RNA interference therapeutic, has been shown to inhibit lymph node tasis in orthotopic prostate cancer mouse models. The aim of this study is to elucidate the acologic activity of Atu027 in inhibiting hematogenous metastasis to the target organ lung in four nt preclinical mouse models. erimental Design: Atu027 compared with vehicle or control small interfering RNA ...

PURPOSE A clinical feature of myxofibrosarcoma is local recurrence, but knowledge about distant metastasis is sparse. We evaluated the tendency of clinical and histological features of metastasis in myxofibrosarcoma patients. METHODS Fifty-eight patients with myxofibrosarcoma were treated in our hospitals, and a total of 16 consecutive patients with distant metastases were included in this re...

1. Gupta V, Bhutani N, Marwah Sen R. Scalp metastasis as an initial presentation of lung adenocarcinoma : A case report and literature review. Int J Surg Case Rep. 2017;41:327-331. doi:10.1016/j.ijscr.2017.10.060 CrossRef Google Scholar

The 5 year survival rate of lung cancer is <20%, with most patients dying from distant metastasis. However, the molecular mechanisms underlying lung cancer invasion and metastasis have not been fully characterized. In this study, we found that fibulin-3, a fibulin family extracellular matrix protein, functions as a suppressor of lung cancer invasion and metastasis. Fibulin-3 was downregulated i...

Metastasis from colorectal carcinoma occurs by either lymphatic or hematogenous spread. The most common sites of colorectal metastasis are the liver and lung. Involvement of the skin, muscles and bones are quite rare. The prognosis in such patients is usually poor. Herewith, we are reporting a case of colonic carcinoma who had cutaneous metastasis, muscular involvement and diffuse skeletal meta...

PURPOSE The lung is the second most common site of metastasis from colorectal cancer. Of all patients who undergo a curative resection for colorectal cancer, 10% to 15% will develop lung metastasis. As a hepatic resection of colorectal liver metastases results in improved survival, many reports have suggested that a pulmonary resection of a colorectal lung metastasis would also improve survival...

The lung is a distant metastatic site of gynecologic cancers. These metastases have clinical characteristics which can be solitary, multiple, solid, or manifest by pleural effusion. Diagnosing and managing metastasis challenging because each type gynecological cancer has different characteristics. Some cancers tumor markers that help diagnose metastasis; however, others do not them. options for...

Convenient and reliable multiple organ metastasis model systems might contribute to understanding the mechanism(s) of metastasis of lung cancer, which may lead to overcoming metastasis and improvement in the treatment outcome of lung cancer. We isolated a highly metastatic subline, PC14HM, from the human pulmonary adenocarcinoma cell line, PC14, using an in vivo selection method. The expression...

Background This study identifies the overall survival status of lung cancer patients with bone metastasis and metastasis patterns. Poor prognostic factors were identified to develop a scoring system for estimating survival period after bone metastasis. Methods A retrospective cohort analysis was performed at Chiang Mai University for the period January 1, 2006 and December 31, 2013. Time-to-e...

Downloa pose: Atu027, a novel RNA interference therapeutic, has been shown to inhibit lymph node tasis in orthotopic prostate cancer mouse models. The aim of this study is to elucidate the acologic activity of Atu027 in inhibiting hematogenous metastasis to the target organ lung in four nt preclinical mouse models. erimental Design: Atu027 compared with vehicle or control small interfering RNA ...