forty-one wild sheep (ovis ammon orintalis) from kabodan island of national park of urmialake (north-west of iran), were examined during a period of six months from october 2002 tomarch 2003, for helminthes and coccidian infection. the numbers of oocyst and eggs per gram offaeces (opg & epg) were determined by the centrifuge flotation technique using saturated sugarsolution. the rate of inf...

BACKGROUND Pseudomonas aeruginosa (PA) infection is involved in various lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease. However, treatment of PA infection is not very effective in part due to antibiotic resistance. α1-antitrypsin (A1AT) has been shown to reduce PA infection in humans and animals, but the underlying mechanisms remain unclear. The goal of our stud...

Pseudomonas aeruginosa is a leading cause of pneumonia, and many components of the innate immune system have been proposed to exert important effects in preventing lung infection. However, a vigorous experimental system to identify an overriding, key effector mediating innate immunity to lung infection has not been utilized. As many of the important components of innate immunity are involved in...

A 68 years old man with prostate carcinoma was referred for 68Ga-PSMA PET/CT scan because of recent significant rise of PSA. He complained of muscle weakness and fatigue, since 3 weeks before the scan, without dyspnea or shortness of breath. In his 68Ga-PSMA-611 PET/CT study, widespread skeletal metastasis, as well as liver involvement were noticed. Also, multiple bilatera...

OBJECTIVE Pseudomonas aeruginosa has been suggested as a major determinant of poor pulmonary outcomes in cystic fibrosis (CF), although other factors play a role. Our objective was to investigate the association of early childhood Pseudomonas infection on differences in lung function in adolescence with CF. METHODS Two populations of subjects with CF were studied: from the Gene Modifier Study...

Abstract Prostaglandin D2 (PGD2) may play an anti-inflammatory role in the lung during respiratory viral infection, but little is known about expression of its receptors (PPAR-γ, DP1, and DP2) or mechanism action. Adult C57BL/6 mice were infected with Sendai virus (500 pfu /g body weight), a natural mouse pathogen that infects airway epithelial cells. Immunostaining uninfected lungs showed PPAR...

Avian influenza A/H7N9 virus infection causes pneumonia in humans with a high case fatality rate. However, virus-induced modulation of immune responses is being recognized increasingly as a factor in the pathogenesis of this disease. In this study, we compared the pathogenicity of A/H7N9 infection in BALB/c and C57BL/6 mouse models, and investigated the putative involvement of proinflammatory c...

An adenovirus 5 vector encoding for mouse interferon alpha, subtype 5 (mDEF201) was evaluated for efficacy against lethal vaccinia virus (WR strain) respiratory infections in mice. mDEF201 was administered as a single intranasal treatment either prophylactically or therapeutically at doses of 10(6) to 10(8) plaque forming units/mouse. When the prophylactic treatment was given at 56 days prior t...

Lung volume equipment and infection control. J.L. Clausen. ©ERS Journals Ltd 1997. ABSTRACT: As part of the consensus workshop regarding lung volume measurements for the American Thoracic Society and European Respiratory Society, this background paper reviews mechanisms and risks of cross-infection resultant from performing measurements of absolute lung volumes either by body plethysmography, g...

Common Variable Immunodeficiency (CVID) is a heterogeneous group of diseases progressing with recurrent infections. This disease should be considered in cases experiencing lung infection, otitis media, rhinosinusitis, and urinary tract infection. Since it generally seen the childhood age group, diagnosis adults may delayed. A case, which was followed up our clinic characterized by upper respira...