نتایج جستجو برای: lung function impairment
تعداد نتایج: 1579717 فیلتر نتایج به سال:
Background: C-reactive protein (CRP), a marker of systemic inflammation, is a powerful predictor of adverse cardiovascular events. Respiratory impairment is also associated with cardiovascular risk. Although some studies have found an inverse relationship between lung function and markers of systemic inflammation, only one study has reported a relationship between lung function and CRP levels. ...
OBJECTIVE To test the effect of heart disease and heart surgery on lung function. DESIGN A pulmonary function study of children undergoing surgery for atrial septal defect (ASD). SETTINGS University hospital. PATIENTS 26 children tested before surgery (at mean (SD) age 11.8 (3.8) years) and 24 patients tested 1.8 (0.2) years after surgical correction. METHODS Lung volumes, lung elastici...
BACKGROUND The immune mechanisms associated with infection-induced disease exacerbations in asthma and COPD are not fully understood. Toll-like receptor (TLR) 3 has an important role in recognition of double-stranded viral RNA, which leads to the production of various inflammatory mediators. Thus, an understanding of TLR3 activation should provide insight into the mechanisms underlying virus-in...
Low dose methotrexate treatment (MTX) has been proposed as a potentially promising treatment for primary biliary cirrhosis (PBC), which accounts for many of the liver transplantations in the USA. However, methotrexate treatment has been found to contribute to lower lung function in conditions other than PBC, and if it occurs concomitant with treatment of PBC, could exacerbate the reduced lung f...
Impairment of lung function with selective beta-1 blocking drugs has been repeatedly demonstrated in guinea pigs, normal subjects and asthmatic patients. The effects of several beta blockers, propranolol (non-selective), atenolol (beta-1 selective), IPS 339 (beta-2 selective) on histamine-induced bronchoconstriction have been investigated in 30 anaesthetized and mechanically ventilated guinea p...
OBJECTIVES Occupational exposure to wood dust has been shown to cause several respiratory disorders, such as allergic rhinitis, chronic bronchitis, asthma, sino-nasal adenocarcinoma, and impairment of lung function. The aim of the study was to estimate lung function (in the woodworking industry) among workers employed by wood processing, who run the risk of being expose to wood dust. METHODS ...
Background and Objective: Pelvic girdle and respiratory muscles weakness and hyperglycemia are associated with reduced lung capacity. Therefore, the aim of this study was to investigate the effect of core muscles strengthening on pulmonary function in obese women with type II diabetes. Materials and Methods: The population of the research were all women with diabetes type II in District 2 o...
Combined Effects of in Utero and Adolescent Tobacco Smoke Exposure on Lung Function in C57Bl/6J Mice
BACKGROUND Fetal determinants of airway function, such as in utero exposure to maternal cigarette smoke (CS), may create a predisposition to adult airflow obstruction and chronic obstructive pulmonary disease (COPD) in adulthood. It has been suggested that active smoking in adolescence and preexisting airflow obstruction have synergistic deleterious effects. OBJECTIVE We used a mouse model to...
Current knowledge about factors determining outcome of asthma is limited, but observations over the last few decades suggest that active asthma has a negative impact on the longitudinal changes in lung function. This review aims to give an overview of the present knowledge concerning longitudinal changes in lung function, including clinical markers for distinctly poor outcome with regard to lun...
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