We used a cylindrical model for the left ventricle contracting both radially and longitudinally to show how the ejection fraction is related to different variables that describe the ventricular geometry. The relations during ventricular contraction between wall thickening, midwall radius shortening and longitudinal shortening are used to derive precise formulas for the calculation of ventricula...

Cross-sectional echocardiography is a new noninvasive technique for imaging the heart. We developed a method for using mechanical cross-sectional echocardiograms (sector scans) to determine left ventricular volumes and ejection fraction. Using left ventricular cineangiography as a standard, sector scan ejection fraction correlated better (r = 0.93) than M-mode echocardiography by any of three e...

OBJECTIVES This study was undertaken to determine whether quinidine pharmacodynamics are altered in the presence of left ventricular dysfunction. BACKGROUND Left ventricular function is an independent predictor of antiarrhythmic drug efficacy. However, the effects of left ventricular dysfunction on the pharmacodynamics of antiarrhythmic drugs have not been studied extensively. METHODS Signa...

Septic shock in humans is usually characterized by a high cardiac output, a low systemic vascular resistance, reversible depression of left ventricular ejection fraction, and transient left ventricular dilatation. The relationship of left ventricular to right ventricular function in septic shock is poorly understood. To evaluate right ventricular vs left ventricular performance and to evaluate ...

30 patients with delayed contrast enhancement in patterns suggestive of myocardial infarctions were reviewed. Infarct mass was quantitatively measured using short axis images obtained in the delayed phase of gadopentetate administration. Left ventricular mass and ejection fraction were measured using short axis, steady state free precession images. A relationship is drawn between increased mass...

Quantitative assessment of left ventricular function was performed by single plane cineangiography in I3 patients with ischaemic heart disease without clinical heart failure. As compared with normal controls, 7 of I3 patients had a reduced ejection fraction and 'normalized' ejection rate, suggesting impaired left ventricular function. These patients could not be differentiated clinically in any...

BACKGROUND Left ventricular myocardial performance index is a Doppler-derived parameter of nongeometrical ventricular function that measures both systolic and diastolic function of the left ventricle. The objective of this study was to compare prognostic value of left ventricular myocardial performance index with global left ventricle function in patients undergoing coronary artery bypass graft...

The effects of preload augmentation on left ventricular output (Frank-Starling mechanism), ejection fraction, and the relationship between pulmonary wedge pressure and end-diastolic volume were studied in 15 patients immediately after myocardial revascularization. The patients were studied under morphine sulfate anesthesia with the chest temporarily closed. Sequential measurements of radionucli...