antioxidants have protective effects against free radicals-induced neural damage in parkinson's disease (pd). we examined the effects of ellagic acid (ea) on locomotion, pallidal local eeg, and its frequency bands' power and also cerebral antioxidant contents in a rat model of pd induced by 6-hydroxidopamine (6-ohda). 6-ohda (16 µg/2µ l) was injected into the right medial forebrain bundle (mfb)...

Genetic approaches using temporal and brain region-specific restricted gene deletions have provided a wealth of insight in the brain regions and temporal aspects underlying spatial and associative learning. However, for locomotion such extensive studies are still scarce. Previous studies demonstrated that Camk2b(-/-) mice, which lack the β isoform of Calcium/Calmodulin-dependent protein kinase ...

BACKGROUND In today's porcine industry, lameness has a major welfare and economic impact, and is often caused by osteochondrosis (OC). The etiological factors of the disease have been studied in depth, however, to this day, little is known about the natural course of the disorder and how it can be detected at an early stage in pigs. The aim of this pilot study was to assess the potential of thr...

To investigate the association between locomotion score and types of hoof lesion, cows from 91 selected dairy herds in southern Chile were studied. The locomotion score was recorded for all of the lactating cows (n=10,699). The mean prevalence of lame cows, when all locomotion scores >1 were included was 33.2% in large herds and 28.7% in small herds. There were 39.7%, 42%, 17.9% and 0.4% cows w...

3D Virtual Environments (VE) are becoming popular as a tool for cognitive, functional and psychological assessment. Navigation in these environments is recognized as one of the most difficult activities in 3D Virtual Environments (VE). Users unfamiliar to 3D games, specially elder persons, get puzzled when they try to virtually move an avatar through these environments. Their inability to navig...

Oscillatory rhythms in local field potentials (LFPs) are thought to coherently bind cooperating neuronal ensembles to produce behaviors, including locomotion. LFPs recorded from sites that trigger locomotion have been used as a basis for identification of appropriate targets for deep brain stimulation (DBS) to enhance locomotor recovery in patients with gait disorders. Theta band activity (6-12...