Background & Aim: The human body has the liver as one of its largest organs. It serves as the major site for metabolism and excretion. Injury to the liver or impairment of its functions may complicate one’s health and therefore, constitutes one of the serious public health challenges. The ethanol seed extract of Citrus paradisi Macfad (CPE) was carried out to evaluate ...

The effect of V. vinifera seeds on carbohydrate metabolizing enzymes and other enzymes of the liver in diabetes is currently unknown. We therefore investigated changes in the activity levels of these enzymes following V. vinifera seed extract administration to diabetic rats. Methods. V. vinifera seed ethanolic extract (250 and 500 mg/kg/day) or glibenclamide (600 μg/kg/day) was administered to ...

Arnebia euchroma is from Boraginaceae family. Various therapeutic effects have been reported for different species of this plant. The aim of this study was to investigate antioxidant activity of hydroalcoholic extract of the root of A. euchroma and its protective effect on hepatotoxicity induced by CCl4 in mice. In this experimental study, A. euchroma was extracted with ethanol solvent by macer...

This study was carried out to investigate the effect of alcoholic extract of Lagerstroemia speciosa (L) pers. against carbon tetrachloride (CCl4) induced liver fibrosis in male albino Wistar rats (150-200gm). Liver fibrosis was induced by twice/week administration of CCl4 at a dose of 1ml/kg body weight, mixed with an equal volume of corn oil. The extent of liver fibrosis was assessed by the co...

background: acantholimon gilliati turril(plumbaginaceae) is used in variety of diseases including hepatic ailments in the west region of iran. aim of the study: to investigate the hepatoprotective effect of methanoilc extract (me) of a. gilliati on formaldehyde (fa) induced liver injury in adult male mice.materials and methods: fifty six adult male mice were divided into 8 groups. in control gr...

hepatoprotective efficacy of propolis extract (honeybee hive product, 200 mg/kg, p.o.) was studied against carbon-tetrachloride-(ccl 4, 0.15 ml/kg, i.p.) induced biochemical and histopathological changes. silymarin, a known hepatoprotective drug was used as a positive control. subchronic exposure to ccl 4 for 3 weeks (5 days a week) caused sharp elevation in the activity of liver enzymes i.e. ,...

Objective: Diazinon causes oxidative stress and dysfunction of the liver. This study was undertaken to evaluate the effects of the hydroalcoholic extract of Terminalia chebula, on some biochemical and histopathological parameters of liver tissue in diazinon-administered rats. Materials and Methods: Wistar rats were orally administered with 25 mg/kg body weight diazinon. Vehicle (distilled water...

Non-alcoholic fatty liver induces many complications to the liver tissue and also serum related parameters. Medicinal plants are the safe therapeutic strategy for the treatment of diseases. In this regards, the present study was conducted to evaluate the effect of Tribulus terrestris (T. terrestris) extract on non-alcoholic fatty liver in rats. In this experimental study, thirty male Wistar rat...

background: garcinia kola seed is consumed indiscriminately in nigeria without recourse to its potential toxicity. therefore, this study was aimed at assessing the toxicity of the aqueous extract of g. kola seeds on selected tissues of male rats.  methods: thirty male rats (215.00 ± 18.58 g) were assigned into four groups: a, b, c and d which received 0.5 ml of distilled water, 25, 50 and 100 m...