نتایج جستجو برای: liver cells
تعداد نتایج: 1650468 فیلتر نتایج به سال:
aim : in this study, to clarify the smad4blocking impact on fibrosis process, we investigated its down-regulation by shrna on activated human lx-2 cell, in vitro. background : liver fibrosis is a critical consequence of chronic damage to the liver that can progress toward advanced diseases, liver cirrhosis and hepatocellular carcinoma (hcc). different smad proteins play as major mediators in...
Objective(s): Nowadays, examining the toxicity of nanoparticles including the synthesized and functionalized iron nanoparticles using methods like green synthesis is highly considered, due to their increasing usage in various fields of medicine, biology, industrial, and pollution removal. Hence, in this study, the toxicity of the zero valent iron nanoparticles synthesized by plant-Myrtus commun...
purpose a metabolic abnormality such as obesity is a major obstacle in the maintenance of the human health system and causes various chronic diseases including type 2 diabetes, hypertension, cardiovascular diseases, as well as various cancers. this study was designed to summarize the recent scientific knowledge regarding the anti-obesity role of curcumin (diferuloylmethane), which is isolated f...
Background: Bone marrow-derived mesenchymal stem cells (BMMSCs) transplantation has been considered as a promising milestone in liver fibrosis treatment. However, low amounts of homing are a major obstacle. We aimed to investigate the role of melatonin pretreatment in BMMSC homing into experimental liver fibrosis. Methods: BMMSCs were obtained, grown, propagated and preconditioned with 5 µ...
Background : Non-Alcoholic Fatty Liver Disease (NAFLD) is the most common liver disease. NAFLD is characterized by elevated liver enzymes and serum ferritin concentration due to damage and abnormal function of liver cells. Increased level of serum ferritin as a parameter of liver function is commonly observed .The aim of this study was to determine the agreement between serum liver with liver a...
persian sturgeon, acipenser persicus is a native, commercially important and highly steemed fish species in the caspian sea. in this study, effects of nodularin (nodln), a cyclic pentapeptide hepatotoxin, on liver and gill tissues of a. persicus were studied. nodularin was produced in high amounts by nodularia spumigena, a cyanobacterium species during the algal bloom in the caspian sea and was...
background: quercetin is a strong antioxidant and long-term treatment of stz-diabetic animals and it has been shown to reduce oxidative stress. objective: antioxidants have essential effect on spermatogenesis and sperm parameters. enhanced oxidative stress and changes in antioxidant capacity are considered to play an important role in the pathogenesis of chronic diabetes mellitus. methods: ...
stem cell therapy is a powerful technique for the treatment of a number of diseases. stem cells are derived from different tissue sources, the most important of which are the bone marrow (bm), umbilical cord (uc) blood and liver. human uc mesenchymal stem cells (huc-mscs) are multipotent, non-hematopoietic stem cells that have the ability to self-renew and differentiate into other cells and tis...
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