Background Hepatocellular carcinoma (HCC) has an increasing incidence and high mortality. Surgical operation is not a comprehensive strategy for liver cancer. Moreover, tolerating systemic chemotherapy is difficult for patients with HCC because hepatic function is often impaired due to underlying cirrhosis. Therefore, a comprehensive strategy for cancer treatment should be developed. DTL (Cdc10...

Primary liver tumors are a heterogeneous group of malignancies. Besides classical hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), combined and intermediate forms of liver cancer exist and can express stem-cell markers like nuclear cell adhesion molecule (NCAM-1/CD56), c-kit (CD117) or epithelial cell adhesion molecule (EpCAM) together with high proliferative activity. Liver tumors w...

the adhesive interaction between tumor cells and the host cells or the extracellular matrix plays a crucial role in tumor metastasis. to evaluate the mediation of cell adhesion by daphne mucronata, an anti-cancer medicinal plant in iranian folk medicine, the adhesion of thrombin activated human platelets to the cultured monocytes or hl-60 cells was investigated under the effect of the plant ext...

background and aim: basal cell carcinoma (bcc) is the most common skin neoplasm and the most common type of cancer. since the incidence of injury is taken into consideration in the pathologic diagnosis, the study of clinical and microscopic views of bcc is of particular importance. the present study aimed at determining the frequency of clinical and microscopic views of bcc in a 10-year period ...

The incidence and mortality of liver cancer increased year by year. Our country presents high incidence of liver cancer. MicroRNAs have tissue sensitivity as tumor biomarkers that play a role by promoting tumor growth as oncogenes or inhibit malignant cell growth as tumor suppressor genes. Studies showed that miR-15b abnormal expression in the tumor and can be treated as one of the tumor molecu...

Objective: Rosa beggeriana Schrenk has been consumed in Iranian traditional medicine. In contrary to its close species (e.g. R. canina), there is no data on its medicinal properties. Therefore, we explored possible cytotoxic effects of R. beggeriana against two cancer cell lines. Materials and Methods: The cytotoxic and anti-pro...

Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticancer effect preventing cancer cell metastasis. We investigate whether the anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-κB/p53-apoptosis signaling pathway. Human liver cancer HepG2 cell were treated with 10, 20, 30...

Cervical cancer, the fourth most common cancer among females in world, ranks second China. In advanced disease, metastases may be commonly present lungs, bones, liver and lymph nodes or elsewhere, but uncommon to skin. this report, a 63-year-old woman was diagnosed as stage IVB cervical squamous cell January 2021. The patient scheduled for concurrent chemoradiotherapy; however, metastatic lesio...

Background: Lung cancer ranks among the most common and most lethal malignancies worldwide. Once vascular or lymphatic invasions occur, metastatic dissemination to distant sites is common. Bone, liver, adrenals, and brain are the most frequent sites of the distant disease. In this study we present a case of squamous cell carcinoma of lung with metastasis of the left knee bursa.Case presentation...