lithium is widely used in medicine as an anti-depressive drug. in spite of abundant literature, questions on the side effects of lithium ions are far from being answered. in this study, the effects of lithium on biochemical parameters related to lipid metabolism were investigated. male wistar rats were treated with different doses of lithium for a period of up to 60 days. blood samples were col...

these experiments examined the effects of pre-test intra dorsal hippocampus (intra-ca1) administration of gabaa receptor agonist and antagonist, muscimol and bicuculline respectively, on state-dependent learning induced by lithium. male nmri mice were trained in a one-trial step-down inhibitory avoidance task, and immediately after training they received ip injections of either saline (10 ml/kg...

On the basis of lithium electrolyte mechanism, modified glassy polymers were developed by adding salts to poly(methyl methacrylate) (PMMA). This review summarizes how rheological and mechanical properties PMMA changed introducing various salts: perchlorate (LiClO4), trifluoroacetate (LiCOOCF3), trifluoromethanesulfonate (LiCF3SO3), nonafluorobutanesulfonate (LiC4F9SO3), bromide (LiBr). It was f...

objective(s) it is believed that the mesenchymal stem cell (msc) differentiation and proliferation are the results of activation of wnt signaling pathway. on the other hand, lithium chloride is reported to be able to activate this pathway. the objective of this study was to investigate the effect of lithium on in vitro proliferation and bone differentiation of marrow-derived msc. materials and ...

objective: the influence of cholinergic drugs on lithium-induced statedependent learning has been investigated in adult male mice. method: a single-trial step-down inhibitory avoidance task was selected. the drugs used in the study were lithium chloride physostigmine , nicotine hydrogen tartrate and scopolamine hydrobromide, atropine sulphate. the drugs were administrated through the peritoneal...

the effect of neuroloptics. carbamacepine and hensmliacepines in treatment of 8.3 patients with acute mania was studied. according to drug types. patients were divided into 5 groups: 1) lithium combined with ilubupridol. 2) lithium combined with one plxenoshiacine 3) lithium combined with two phenothiazines. 4) lithium combined with cubumazepine and 5) lithium combined with benzxliazepines no s...

A 64-year-old woman had suffered from recurrent depressive illnesses, although two attacks of manic behaviour had followed treatment for depression. She was first admitted to hospital in 1954 because of depression. Subsequently she had been admitted on fifteen occasions. As is common in the affective disorders, her attacks had become progressively more frequent and she had spent most of the pre...