background: doxorubicin (dox), an anthracycline antibiotic, is a widely used anticancer agent. in spite of its high antitumor efficacy, the use of dox in clinical chemotherapy is limited due to diverse toxicities, including gonadotoxicity. objective:  we investigated the protective effect of nano-zinc oxide (nzno) as an established antioxidant on dox-induced testicular disorders. materials and ...

Objective : Oral squamous cell carcinoma (OSCC) is considered to be a serious life threatening issue for almost two decades. The objective of this study was to evaluate the over production of lipid peroxidation (LPO) byproducts and disturbances in antioxidant defense system in the pathogenesis of oral cancer. Methods : Lipid peroxidation and antioxidant status in OSCC patients were estimated an...

In this study, we have evaluated the co-application of epibrassinolide (24-EBL) and putrescine (Put) on stress indicators and antioxidant system of Solanum lycopersicum L. grown under salinity stress. EBL and Put application along with NaCl stress showed differential responses in the activities of antioxidant enzymes (superoxide dismutase, catalase and guaiacol peroxidase). Significant increase...

Consumption of high-fat diet (HFD) induces nonalcoholic fatty liver disease (NAFLD) and may lead to multiple complications affecting human health. In the present study, effect of Moringa oleifera leaf extract (MoLE) in alleviating HFD induced liver injury in mice has been reported. Liver histology and serum activity of hepatic marker enzymes i.e. aspartate aminotransferase (AST), alanine aminot...

The purpose of the work was to reveal role sex factors in processes lipid peroxidation (LPO) against background chronic ethanol-tetrachloromethane-induced liver damage and hepatotropic effects triple antiulcer therapy cryopreserved placenta extract (CEP). Chronic induced by introduction a CCl4 solution combination with an ethanol for 45 days. content reactants thiobarbituric acid (TBA-active pr...

One of the most widespread aquatic organisms in rivers and estuarine ecosystems, world, is Asian clam Corbiculafluminea. This clam, that can adapt to environmental changes, an invasive species several areas it was adopted as a model for toxicity tests. study evaluated effects exposure cadmium (Cd), microplastics (MPs) their mixtures on C. fluminea. The oxidative stress responses, lipid peroxida...

The effect of biofloc (BFT) and clear water (CW) at low (ls) high-water salinity (hs) in wild juveniles Penaeus setiferus were evaluated. Four treatments implemented: hsBFT, lsBFT, hsCW, lsCW. After 45 days, final weight (FW), gain (WG), hepatosomatic index (HSI), survival rate (SR) Antioxidant activity muscle hepatopancreas measured: superoxide dismutase (SOD), catalase (CAT), glutathione-S tr...

The present investigation was designed to investigate the combined effects of Gymnema sylvestre (GS) and glibenclamide (GLB) in the regulation of alloxan induced diabetes mellitus and tissue lipid peroxidation in mice. Ethanolic extract of GS (600 mg/kg body weight) and GLB (500 μg/kg body weight) were treated either alone or in combination for 15 days in alloxan (200 mg/kg body weight) induced...