We study the nonequilibrium motion of an elastic string in a two dimensional pinning landscape using Langevin dynamics simulations. The relaxation of a line, initially flat, is characterized by a growing length L(t) separating the equilibrated short length scales from the flat long distance geometry that keeps a memory of the initial condition. We show that, in the long time limit, L(t) has a n...

We show the importance of finite particle size in microfluidic asymmetric continuous-flow diffusion arrays, specifically the critical nature of the particle size with respect to the barrier gaps. We show that particles much smaller than the barrier gap follow individual field lines through narrow gaps and are poorly fractionated. In contrast, particles comparable to the gap size lose memory of ...

multiple sclerosis (ms) is an inflammatory disorder, in which neurons become demyelinated. to date, its etiology has remained unknown. nevertheless, certain features are inspected to provoke ms. for instance, improper function of immune cells is widely believed to be the basis of such disorder. in this concept, ms is stated as an autoimmune disease, which was asserted by major of studies, as cd...

background: family planning is a lifestyle that is selected voluntarily and is based on the knowledge, attitude and responsible decision making by couples in order to promote the health and welfare of the family and the advancement of the society. in this regard, family planning counseling plays an important role in making informed decisions if used properly and in a responsible way. detection ...

Background The nasal epithelium represents the first barrier against entry of airborne particles into the respiratory system and therefore protects against allergens, pollutants and pathogens. We have previously used the respiratory epithelial cell line 16HBE14oto define factors which can impair the barrier function of the respiratory mucosa. However, cultures of primary epithelial cells obtain...

Abstract In 1963, the late W. F. (“Joe”) Vinen concluded, partly on intuitive grounds, that ab initio creation of a quantized vortex line in superfluid $$^4$$ 4 He is impeded by an energy barrier. We place this prescient insight into context and review subsequent theoretica...

We prove existence, uniqueness and HH older continuity of a stochastic process satisfying a one dimensional wave equation driven by space-time white noise. Then we discuss a barrier problem for these stochastic wave equations in the case where we have only the stochastic term forcing the equation and where we have zero initial conditions. In a barrier problem we ask for the probability that the...

BACKGROUND Knowledge about the impact of each central line insertion bundle on central line-associated bloodstream infection (CLABSI) is limited. METHODS A quality-improvement intervention, including education, central venous catheter (CVC) insertion bundle, process and outcome surveillance, have been introduced since March 2013. Outcome surveillances, including CLABSI per 1,000 catheter-days...

Epithelial cells line the intestinal mucosa and form an important barrier to a wide array of noxious substances in the lumen. Disruption of the barrier integrity occurs commonly in various pathologies. Long noncoding RNAs (lncRNAs) control diverse biological processes, but little is known about the role of lncRNAs in regulation of the gut permeability. Here we show that the lncRNA SPRY4-IT1 reg...

The intestinal epithelial barrier is indispensable to our immune system. Defects in this barrier function have been observed in intestinal disorders such as inflammatory bowel diseases, food allergies, and celiac diseases. Therefore, the modulation of the barrier function is currently viewed as a potentially positive pharmacological outcome. This review describes a unique peptide, Asn-Pro-Trp- ...