Lactoferrin (LF) is an 80 kD iron-binding glycoprotein that is most highly produced in human and bovine milk and is also widely distributed in mammals. Researches of more than 70 years on lactoferrin prove that the molecule, as a nutritional molecule for mammals, possesses several physiological roles, including maintaining iron absorption, anti-microbial activity and immune modulation. Recent s...

Hermaphrodites carrying dominant mutations in the gene egl-41 (egl, egg-laying defective) lack the hermaphrodite-specific HSN neurons but have the male-specific CEM neurons and therefore are weakly masculinized (1, 2). Our analyses with a deficiency (nDf42) and a duplication (ctDp8) that span the egl-41 locus indicate that egl-41 is not haplo-insufficient and that the dominant mutations cause a...

The iron-binding protein lactoferrin (Lf) present in blood is metabolized by the liver. Isolated rat hepatocytes vigorously endocytose bovine Lf via recycling Ca2(+)-dependent binding sites, but the uptake of iron from Lf by hepatocytes has not been examined. In this study, isolated rat hepatocytes were incubated with radiolabelled bovine Lf (125I-Lf, 59Fe-Lf or 125I-59Fe-Lf) at 37 degrees C, t...

Logical frameworks have enjoyed wide adoption as meta-languages for describing deductive systems. While the techniques for representing object languages in logical frameworks are relatively well understood, languages and techniques for metaprogramming with them are much less so. This paper presents work in progress on a programming language called Rogue-Sigma-Pi (RSP), in which general programs...