introduction: binding a monoclonal antibody to tumor associated antigens is an effective method for cancer therapy because these agents can specifically target malignant cells, in fact monoclonal antibodies are effective agents for diagnosis, grading and treatment of different kinds of cancers. methods: in this research, a new monoclonal antibody against colon cancer cells was prepared and anti...

We use stone tool refitting to assess palimpsest formation and stratigraphic integrity in the basal units of the Gruta da Oliveira archeo-stratigraphic sequence, layers 15-27, which TL and U-series dating places in late Marine Isotope Stage (MIS) 5 or early MIS 4. As in most karst contexts, the formation of this succession involved multiple and complex phenomena, including subsidence, bioturbat...

PURPOSE The effectiveness of nonsteroid topical agents for the prevention of acute dermatitis during adjuvant radiotherapy for breast carcinoma has not been demonstrated. The goal of this study was to compare the effectiveness of calendula (Pommade au Calendula par Digestion; Boiron Ltd, Levallois-Perret, France) with that of trolamine (Biafine; Genmedix Ltd, France), which is considered in man...

this study redescribes an arthroscopic bridge technique for repair of avulsion of the posterior cruciate ligament. the procedure is performed step-to-step. in this technique we created two bone tunnels in the anterior aspect of the tibia and inferior medial of the tibia tuberosity and then create suture fixation of the fragment using the suture bridge. the arthroscopic bridge technique was used...

the membrane separation technology by relying on microfiltration ultrafiltration, and reverse osmosis methods are becoming more important among consulting engineers, designers of environmental pollution control system, and industrial factories. the advantages of this technology together with its emphasis on recycling the fluid to the system and reusing the membranes have caused the membranes to...

BACKGROUND Safe drinking water is essential for well-being. Although microbiological contamination remains the largest cause of water-related morbidity and mortality globally, chemicals in water supplies may also cause disease, and evidence of the human health consequences is limited or lacking for many of them. OBJECTIVES We aimed to summarize the state of knowledge, identify gaps in underst...

La fouille du site de la Route Jaunour à Boulazac Isle Manoire (Dordogne), menée dans le cadre d’une opération d’archéologie préventive, livre un nouveau témoin d’occupation vallée l’Isle au Paléolithique moyen récent. Le site, dont l’emprise s’étend sur près 1000 m2, est localisé en pied pente base d’un plateau crayeux surplombant l’Isle. nappe mobilier s’insère une unité graveleuse interprété...

Since its discovery and initial description in the 1960s, the penetrating lesion to the left ninth rib of the Shanidar 3 Neandertal has been a focus for discussion about interpersonal violence and weapon technology in the Middle Paleolithic. Recent experimental studies using lithic points on animal targets suggest that aspects of weapon system dynamics can be inferred from the form of the bony ...