We present the CT and MR imaging findings in acute methanol intoxication in a 35-year-old man who was admitted to the emergency department with weakness, blurred vision, mild bilateral areactive mydriasis, and a progressive decrease in the level of consciousness. CT and MR imaging showed bilateral putaminal hemorrhagic necrosis and subcortical white matter lesions with peripheral contrast enhan...

Australian Hardboards (AHL) own and operate a wet process hardboard manufacturing plant in Queensland, Australia, that generates a significant quantity of process water effluent during the production of Masonite. AHL management recognised that there were significant opportunities to reduce water and energy usage in the process without adversely affecting product quality. Sinclair Knight Merz (S...

During quorum sensing in the plant pathogen Pantoea stewartii subsp. stewartii, EsaI, an acyl-homoserine lactone (AHL) synthase, and the transcription factor EsaR coordinately control capsular polysaccharide production. The capsule is expressed only at high cell density when AHL levels are high, leading to inactivation of EsaR. In lieu of detailed structural information, the precise mechanism w...

N-acyl-homoserine lactones (AHLs) are small diffusible molecules called autoinducers that mediate cell-to-cell communications. Enzymatic degradation of AHLs is a promising bio-control strategy known as quorum-quenching. To improve the quorum-quenching activity of a thermostable esterase Est816, which had been previously cloned, we have engineered the enzyme by random mutagenesis. One of the mut...

N-Acylhomoserine lactone (AHL)-acylase (also known as amidase or amidohydrolase) is a class of enzyme that belongs to the Ntn-hydrolase superfamily. As the name implies, AHL-acylases are capable of hydrolysing AHLs, the most studied signaling molecules for quorum sensing in Gram-negative bacteria. Enzymatic degradation of AHLs can be beneficial in attenuating bacterial virulence, which can be e...

A novel group of nitrogen-fixing plant-associated Burkholderia species has emerged in the last few years. The purpose of this investigation was to determine if these species possess an N-acylhomoserine lactone (AHL) quorum-sensing (QS) cell-cell signalling system, and whether it is important for nitrogen fixation and other phenotypic features in Burkholderia kururiensis. It was determined that ...

Major depressive disorder (MDD) is a leading world-wide psychiatric disorder with high recurrence rate, therefore, it is desirable to identify current MDD (cMDD) and remitted MDD (rMDD) for their appropriate therapeutic interventions. In the study, 19 cMDD, 19 rMDD and 19 well-matched healthy controls (HC) were enrolled and scanned with the resting-state functional magnetic resonance imaging (r...

The four large Swedish lakes Vänern, Vättern, Mälaren and Hjälmaren differ in many respects, not least in drainage area characteristics and basin morphometry (1). The differences also include water quality. Since nutrient chemistry of phosphorus (P) and nitrogen (N) in the lakes is of major concern, it has been treated by several authors (2–13). The hydrochemical studies started in 1964 and in ...

Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somata 5 6 Mark D. Benton, Amanda H. Lewis, Jason S. Bant, and Indira M. Raman 7 Interdepartmental Neuroscience Program, 8 Interdepartmental Biological Sciences Program, and 9 Department of Neurobiology 10 Northwestern University, 11 Evanston, IL USA 12 13 14 15 16 Word counts: 17 Abstract 248 18 Introduction 476 19 Discussio...

Electroretinogram (ERG) is a time-varying potential which arises from different layers of retina. To be specific, all the physiological signals may contain some useful information which is not visible to our naked eye. However this subtle information is difficult to monitor directly. Therefore the ERG signal features which are extracted and analyzed using computers are highly useful for diagnos...